Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TXN | P10599 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814748 | 0.79 | PDE7A (0.51) | ALDH1A1LMNASMN1; SMN2HPGDHSP90AA1 | |
| SCHEMBL9504735 | 0.78 | CYP19A1 (0.61) | ALDH1A1LMNAMAPTCRHBPCRHR2 | |
| SCHEMBL6926453 | 0.77 | ERN1 (0.48) | ALDH1A1LMNAMAPTCRHBPCRHR2 | |
| SCHEMBL9502669 | 0.76 | CYP19A1 (0.60) | ALDH1A1LMNAMAPTCRHBPCRHR2 | |
| SCHEMBL9502657 | 0.76 | CYP19A1 (0.47) | ALDH1A1LMNAMAPTCRHBPCRHR2 | |
| SCHEMBL14147098 | 0.76 | ALDH1A1 (0.64) | ALDH1A1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL5553609 | 0.75 | ERN1 (0.49) | ALDH1A1LMNAMAPTCRHBPCRHR2 | |
| SCHEMBL10513227 | 0.74 | MAOA (0.50) | ALDH1A1LMNAMAPTHSP90AA1POLB | |
| SCHEMBL26012277 | 0.74 | MAOA (0.50) | ALDH1A1LMNAMAPTHSP90AA1POLB | |
| SCHEMBL29106577 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022032144-A1 | SUBSTRATE ADAPTOR INHIBITORS OF PRMT5 AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2022-02-10 | — | — | WO | disclosed |