Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504735 | 0.88 | CYP19A1 (0.61) | CYP19A1ALDH1A1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL9502669 | 0.87 | CYP19A1 (0.60) | CYP19A1ALDH1A1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL9501608 | 0.83 | GRIA1 (0.47) | CYP19A1ALDH1A1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL9502695 | 0.81 | GRIA1 (0.47) | CYP19A1ALDH1A1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL9502667 | 0.80 | HSP90AA1 (0.54) | CYP19A1ALDH1A1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL9501539 | 0.77 | PSIP1 (0.46) | ALDH1A1SMN1; SMN2PTGS2LMNAHPGD | |
| SCHEMBL4839134 | 0.77 | CYP19A1 (0.79) | CYP19A1ALDH1A1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL29451622 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2CYP3A4ALOX15 | |
| SCHEMBL14864853 | 0.72 | POLB (0.44) | ALDH1A1MAPTSMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL6814748 | 0.71 | PDE7A (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |