SCHEMBL29454103

SCHEMBL29454103

Cc1cccc(N(C)c2cc(Cl)cc(N)c2C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 2/20 0.37
GAA P10253 1/20 0.37
CSF1R P07333 4/20 0.36
SIGMAR1 Q99720 1/20 0.36
EGFR P00533 4/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.35
HSP90AA1 P07900 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPK13 O15264 1/20 0.34
MAPK12 P53778 1/20 0.34
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31723252 1.00 L3MBTL1 (0.39) L3MBTL1KMT2AGAACSF1RSIGMAR1
SCHEMBL29454084 0.89 EGFR (0.44) L3MBTL1KMT2AGAACSF1REGFR
SCHEMBL22232059 0.89 EGFR (0.44) L3MBTL1KMT2AGAACSF1REGFR
SCHEMBL31723209 0.89 EGFR (0.44) L3MBTL1KMT2AGAACSF1REGFR
SCHEMBL29454136 0.86 CHKA (0.42) KMT2AGAACSF1REGFRLMNA
SCHEMBL29454192 0.85 ABCG2 (0.36) KMT2AGAAEGFRMAPK13MAPK12
SCHEMBL31723238 0.85 ABCG2 (0.36) KMT2AGAAEGFRMAPK13MAPK12
SCHEMBL22231907 0.85 ABCG2 (0.36) KMT2AGAAEGFRMAPK13MAPK12
SCHEMBL31723240 0.82 ACHE (0.39) CSF1RSIGMAR1EGFRSMN1; SMN2TSHR
SCHEMBL22232258 0.82 ACHE (0.39) CSF1RSIGMAR1EGFRSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US claimed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US claimed
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS L3MBTL1 881/4885KMT2A 438/4885GAA 1080/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS L3MBTL1 2103/4885KMT2A 3264/4885GAA 2001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.