SCHEMBL29454204

SCHEMBL29454204

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC1C=NC=N1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)[C@@H](C)CC)C(=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)[C@@H](C)O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 1/20 0.61
▸ NPY2R P49146 1/20 0.61
▸ NPY4R P50391 1/20 0.61
▸ NPY5R Q15761 1/20 0.61
▸ GLP1R P43220 13/20 0.57
▸ CXCR4 P61073 2/20 0.55
▸ GCGR P47871 5/20 0.55
▸ GIPR P48546 2/20 0.55
▸ CALCA P06881 1/20 0.55
▸ ECE1 P42892 1/20 0.54
▸ MUS81 Q96NY9 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13613774 0.87 GALR2 (0.59) GLP1RGIPRCALCA
SCHEMBL29370578 0.86 NPY1R (0.67) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29972944 0.85 NPY1R (0.69) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29851285 0.85 CXCR4 (0.64) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30973903 0.84 NPY1R (0.66) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30906424 0.84 NPY2R (0.70) NPY1RNPY2RNPY4RNPY5RGLP1R
Galanin SCHEMBL29352997 0.84 GLP1R (0.67) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30666385 0.83 NPY1R (0.69) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29972984 0.83 NPY1R (0.65) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30041162 0.83 CALCA (0.64) NPY1RNPY2RNPY4RNPY5RGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454115-B Chimeric antigen receptor targeting sialyl lewis a and uses thereof 纪念斯隆-凯特琳癌症中心 2025-06-13 — — CN claimed
CN-119019572-A Enhanced chimeric antigen receptor and uses thereof 纪念斯隆-凯特琳癌症中心 2024-11-26 — — CN claimed
CN-118955737-A Enhanced chimeric antigen receptor and uses thereof 纪念斯隆-凯特琳癌症中心 2024-11-15 — — CN claimed
US-20240166743-A1 ENHANCED CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-05-23 — — US claimed
US-11932690-B2 Enhanced chimeric antigen receptors and uses thereof MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-03-19 — — US claimed
CN-114585641-A Mesothelin CAR and uses thereof 纪念斯隆-凯特琳癌症中心 2022-06-03 — — CN claimed
US-20220125905-A1 MESOTHELIN CARS AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2022-04-28 — — US claimed
EP-3969470-A1 MESOTHELIN CARS AND USES THEREOF Memorial Sloan Kettering Cancer Center (US) 2022-03-23 — — EP claimed
EP-4709745-A1 EXTRACELLULAR VESICLES FOR THE DELIVERY OF PAYLOADS TO EUKARYOTIC CELLS Alaya.Bio Inc. (US) 2026-03-18 — — EP disclosed
EP-4683932-A2 CELLS AND COMPOSITIONS FOR TREATING CANCER Memorial Sloan-Kettering Cancer Center (US) 2026-01-28 — — EP disclosed
US-20260007750-A1 CELLS AND COMPOSITIONS FOR TREATING CANCER MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2026-01-08 — — US disclosed
CN-113454115-B Chimeric antigen receptor targeting sialyl lewis a and uses thereof 纪念斯隆-凯特琳癌症中心 2025-06-13 — — CN disclosed
CN-114585641-B Mesothelin CAR and uses thereof 纪念斯隆-凯特琳癌症中心 2025-05-23 — — CN disclosed
US-20240398866-A1 CELLS EXPRESSING FAS LIGAND AND CFLIP POLYPEPTIDES AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-12-05 — — US disclosed
US-20220401475-A1 COMBINATIONS OF MULTIPLE CHIMERIC ANTIGEN RECEPTORS FOR IMMUNOTHERAPY MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2022-12-22 — — US disclosed
CN-115210254-A Cells expressing C-KIT mutations and uses thereof 纪念斯隆-凯特琳癌症中心 2022-10-18 — — CN disclosed
EP-4069730-A1 CELLS EXPRESSING C-KIT MUTATIONS AND USES THEREOF Memorial Sloan Kettering Cancer Center (US) 2022-10-12 — — EP disclosed
CN-114585641-A Mesothelin CAR and uses thereof 纪念斯隆-凯特琳癌症中心 2022-06-03 — — CN disclosed
US-20220125905-A1 MESOTHELIN CARS AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2022-04-28 — — US disclosed
EP-3969470-A1 MESOTHELIN CARS AND USES THEREOF Memorial Sloan Kettering Cancer Center (US) 2022-03-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007750-A1 CELLS AND COMPOSITIONS FOR TREATING CANCER ICOS, MICA, CD47 NPY1R 275/4885NPY2R 539/4885NPY4R 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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