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Sugi Predict / Compounds / SCHEMBL30973903

SCHEMBL30973903

SCHEMBL30973903

CC(C)CC(NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CN)C(C)O)C(=O)NCC(=O)N1CCCC1C(=O)NC(CCC(N)=O)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(N)=O

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 1/20 0.66
▸ NPY2R P49146 1/20 0.66
▸ NPY4R P50391 1/20 0.66
▸ NPY5R Q15761 1/20 0.66
▸ GLP1R P43220 11/20 0.64
▸ GCGR P47871 3/20 0.64
▸ CXCR4 P61073 2/20 0.64
▸ GIPR P48546 6/20 0.62
▸ CALCA P06881 2/20 0.62
▸ KISS1R Q969F8 2/20 0.61
▸ IL23R Q5VWK5 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30041162 0.98 CALCA (0.64) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29972984 0.96 NPY1R (0.65) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29972944 0.93 NPY1R (0.69) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29370578 0.92 NPY1R (0.67) NPY1RNPY2RNPY4RNPY5RGLP1R
Galantide SCHEMBL31332196 0.89 IL23R (0.62) GLP1RGCGRGIPRIL23R
SCHEMBL29416049 0.87 NPY2R (0.75) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30692431 0.87 NPY2R (0.75) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30527942 0.87 NPY2R (0.75) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29843747 0.87 NPY1R (0.73) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29973367 0.86 CXCL8 (0.62) GLP1RGCGRGIPRIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638483-A1 GALANIN-2 RECEPTOR AGONISTS LifeArc (GB) 2025-10-29 — — EP disclosed
WO-2024132147-A1 GALANIN-2 RECEPTOR AGONISTS LIFEARC (GB) 2024-06-27 — — WO disclosed
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