Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | NNMT | P40261 | 2/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810361 | 0.87 | PTGS1 (0.45) | LMNAMAPK1PDGFRBMKNK1MKNK2 | |
| SCHEMBL22717227 | 0.84 | NNMT (0.49) | RXRAFFAR4FFAR1NNMTNEK2 | |
| SCHEMBL17493598 | 0.83 | OXTR (0.44) | MKNK1MKNK2FFAR4FFAR1NNMT | |
| SCHEMBL2313845 | 0.82 | HTT (0.46) | LMNAMAPK1HTTRAB9ANNMT | |
| SCHEMBL2035417 | 0.81 | PDGFRB (0.52) | MAP4K4LMNAMAPK1HTTRAB9A | |
| SCHEMBL29788124 | 0.81 | PDGFRB (0.52) | MAP4K4LMNAMAPK1HTTRAB9A | |
| SCHEMBL22717189 | 0.79 | ERN1 (0.44) | LMNAMAPK1HTTRAB9AFFAR4 | |
| SCHEMBL2315022 | 0.79 | MAPK1 (0.43) | LMNAMAPK1HTTRAB9ANNMT | |
| SCHEMBL29788196 | 0.79 | FFAR2 (0.55) | MAP4K4LMNAMAPK1HTTRAB9A | |
| SCHEMBL2043863 | 0.79 | FFAR2 (0.55) | MAP4K4LMNAMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976576-A1 | GPR40 AGONISTS | Kallyope, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |