Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103512 | 0.89 | PTPRB (0.46) | PPARGPPARADRD2DRD1DRD4 | |
| SCHEMBL5175800 | 0.89 | PPARG (0.42) | PPARGPPARADRD2DRD1DRD4 | |
| SCHEMBL13114553 | 0.81 | PPARA (0.46) | PPARGPPARADRD2DRD1DRD4 | |
| SCHEMBL4465269 | 0.81 | PTGDR2 (0.48) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8499667 | 0.80 | DRD2 (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL6937296 | 0.79 | CYP4F2 (0.55) | PPARGPPARADRD2DRD1DRD4 | |
| SCHEMBL1904920 | 0.79 | SLC7A5 (0.49) | PDK2CYP1A2 | |
| SCHEMBL27720514 | 0.79 | ALDH1A1 (0.53) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL12621537 | 0.77 | PTPRB (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL12621540 | 0.77 | CA12 (0.40) | PPARGPPARADRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976576-A1 | GPR40 AGONISTS | Kallyope, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |