Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 5/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454657 | 0.89 | PPARG (0.44) | PTPRBDRD2DRD1DRD4DRD5 | |
| SCHEMBL12621537 | 0.83 | PTPRB (0.41) | PTPRBDRD2DRD1DRD4DRD5 | |
| SCHEMBL5175800 | 0.82 | PPARG (0.42) | PTPRBDRD2DRD1DRD4DRD5 | |
| SCHEMBL1904920 | 0.80 | SLC7A5 (0.49) | MEN1KMT2AKDM4EPDK2 | |
| SCHEMBL2899501 | 0.79 | PTPRB (0.38) | PTPRBDRD2DRD1DRD4DRD5 | |
| SCHEMBL13114553 | 0.79 | PPARA (0.46) | PTPRBDRD2DRD1DRD4DRD5 | |
| SCHEMBL28808224 | 0.79 | CTRB1 (0.50) | PTPRBMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL20103587 | 0.78 | PTPRB (0.40) | PTPRBMEN1KMT2A | |
| SCHEMBL20103531 | 0.78 | PDK1 (0.48) | PTPRBMEN1KMT2APTPN1PDK1 | |
| SCHEMBL18511728 | 0.78 | CA12 (0.45) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |