Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.55 |
| ▸ | TOP1 | P11387 | 4/20 | 0.51 |
| ▸ | CYCS | P99999 | 3/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17906212 | 0.91 | TERT (0.47) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL25566046 | 0.91 | TERT (0.47) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL17904265 | 0.87 | TERT (0.47) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL31169674 | 0.85 | TERT (0.50) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL12190732 | 0.84 | TERT (0.49) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL8031578 | 0.84 | TERT (0.49) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL2531376 | 0.84 | TERT (0.49) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL16978969 | 0.84 | TERT (0.49) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL8907605 | 0.83 | ABCG2 (0.52) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL29414382 | 0.82 | TERT (0.57) | TERTTOP1CYCSABCG2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230023927-A1 | IMMUNOGLOBULIN CHIMERIC MONOMER-DIMER HYBRIDS | BIOVERATIV THERAPEUTICS INC (US) | 2023-01-26 | — | — | US | disclosed |
| US-11401322-B2 | Immunoglobulin chimeric monomer-dimer hybrids | BIOVERATIV THERAPEUTICS INC. (US) | 2022-08-02 | — | — | US | disclosed |
| EP-2361932-B2 | Immunoglobulin chimeric monomer-dimer hybrids | BIOVERATIV THERAPEUTICS INC (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3978508-A1 | IMMUNOGLOBULIN CHIMERIC MONOMER-DIMER HYBRIDS | Bioverativ Therapeutics Inc. (US) | 2022-04-06 | — | — | EP | disclosed |