Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TOP1 | P11387 | 3/20 | 0.51 |
| ▸ | CYCS | P99999 | 4/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908945 | 0.85 | ABCG2 (0.46) | ABCG2TOP1CYCSPDE3BPDE3A | |
| SCHEMBL8865488 | 0.84 | MAPT (0.55) | ABCG2TOP1CYCSPDE3BPDE3A | |
| SCHEMBL14629716 | 0.84 | F9 (0.43) | ABCG2TOP1CYCSPDE3BPDE3A | |
| SCHEMBL29558419 | 0.83 | TOP1 (0.61) | ABCG2TOP1CYCSPDE3BPDE3A | |
| SCHEMBL3794157 | 0.83 | TOP1 (0.61) | ABCG2TOP1CYCSPDE3BPDE3A | |
| SCHEMBL14599691 | 0.83 | PDE3B (0.41) | ABCG2TOP1CYCSPDE3BPDE3A | |
| SCHEMBL29454950 | 0.83 | TERT (0.55) | ABCG2TOP1CYCSKDM4EALDH1A1 | |
| SCHEMBL22375349 | 0.81 | PDE3B (0.45) | ABCG2TOP1CYCSPDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL8865004 | 0.80 | TOP1 (0.53) | ABCG2TOP1CYCSENPP2TERT | |
| SCHEMBL10730297 | 0.80 | MEN1 (0.57) | ABCG2TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | claimed |