Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | CHKA | P35790 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.51 |
| ▸ | NCF1 | P14598 | 3/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036271 | 1.00 | PKM (0.68) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL1043251 | 0.86 | NCF1 (0.70) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL29455008 | 0.86 | MEN1 (0.60) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL30058999 | 0.86 | NCF1 (0.70) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL1042082 | 0.85 | NCF1 (0.68) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL1042083 | 0.85 | NCF1 (0.68) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL31167362 | 0.83 | MEN1 (0.56) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL28972104 | 0.83 | DRD3 (0.72) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL30060911 | 0.83 | MEN1 (0.56) | PKMALOX15CASP1HSD17B10CHKA | |
| SCHEMBL5025316 | 0.81 | PKM (0.68) | PKMALOX15CASP1HSD17B10CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386511-B2 | METHODS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2024-03-20 | — | — | EP | claimed |