SCHEMBL571602

SCHEMBL571602

CC(Oc1ccc(Cl)c2cccnc12)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.63
ALOX12 P18054 3/20 0.63
TDP1 Q9NUW8 2/20 0.63
CYP3A4 P08684 1/20 0.63
GAA P10253 2/20 0.59
PKM P14618 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
HTT P42858 1/20 0.53
L3MBTL1 Q9Y468 3/20 0.52
CCR6 P51684 2/20 0.52
HSP90AA1 P07900 2/20 0.52
MAPT P10636 5/20 0.52
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
TSHR P16473 2/20 0.49
HPGD P15428 1/20 0.49
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168947 0.86 KDM4E (0.62) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL9282530 0.84 KDM4E (0.59) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL571223 0.83 KDM4E (0.59) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL3454271 0.83 KDM4E (0.55) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL30112294 0.83 KDM4E (0.55) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL13625112 0.83 KDM4E (0.60) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL29456554 0.82 KDM4E (0.54) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL599824 0.82 KDM4E (0.54) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL27466936 0.82 KDM4E (0.67) KDM4EALOX12TDP1CYP3A4GAA
SCHEMBL571825 0.81 KDM4E (0.60) KDM4EALOX12TDP1CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115996638-A Substituted N-phenyluracils and salts thereof and their use as herbicidal agents 拜耳股份有限公司 2023-04-21 CN disclosed
CN-115989255-A Aqueous capsule suspension concentrate containing biodegradable ester groups 拜耳公司 2023-04-18 CN disclosed
US-10301257-B2 Use of acylsulfonamides for improving plant yield BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-05-28 US disclosed
US-9848602-B2 Use of prothioconazole to induce host defence responses BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-12-26 US disclosed
US-9609863-B2 Herbicide/safener compositions containing N-(tetrazol-5-yl) aryl carboxylic acid amides and N-(triazol-5-yl) aryl carboxylic acid amides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-04-04 US disclosed
US-9332759-B2 Herbicide safener compositions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-05-10 US disclosed
US-20150373975-A1 USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-12-31 US disclosed
US-20150291518-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-15 US disclosed
US-8912124-B2 Use of derivatives of (1-cyanocyclopropyl)phenylphosphinic acid, esters thereof and/or salts thereof for enhancing tolerance in plants to abiotic stress BAYER CROPSCIENCE AG (DE) 2014-12-16 US disclosed
EP-2600720-B1 PESTICIDAL TREATMENT COMPOSITIONS GOWAN COM INTERNAC E SERVICOS LIMITADA (PT) 2014-11-26 EP disclosed
US-20070015662-A1 Herbicide/safener combination BAYER CROPSCIENCE GMBH (DE) 2007-01-18 US disclosed
US-20060276342-A1 Herbicidal compositions BAYER CROPSCIENCE GMBH (DE) 2006-12-07 US disclosed
US-7135434-B2 Herbicidally active composition comprising a mixture of A. a herbicidally active amount of one or more compounds of the HOECHST SCHERING AGREVO GMBH (DE) 2006-11-14 US disclosed
US-20060240984-A1 Herbicidal compositions PALLETT KEN 2006-10-26 US disclosed
US-7101827-B2 Herbicides comprising benzoylcyclohexanediones and safeners AVENTIS CROPSCIENCE GMBH (DE) 2006-09-05 US disclosed
US-20050233906-A1 Oil suspension concentrate BAYER INTELLECTUAL PROPERTY GMBH (DE) 2005-10-20 US disclosed
US-20050070437-A1 Herbicide combinations comprising specific sulfonamides BAYER CROPSCIENCE GMBH (DE) 2005-03-31 US disclosed
US-6864217-B2 Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice HOECHST SCHERING AGREVO GMBH (DE) 2005-03-08 US disclosed
US-20040224848-A1 Herbicides comprising benzoylcyclohexanediones and safeners AVENTIS CROPSCIENCE GMBH (DE) 2004-11-11 US disclosed
US-20040157739-A1 Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators BAYER CROPSCIENCE AG (DE) 2004-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060240984-A1 Herbicidal compositions DDT, GLRX3, GPX1 KDM4E 2233/4885ALOX12 2360/4885TDP1 2575/4885
US-20050070437-A1 Herbicide combinations comprising specific sulfonamides DDT, B2M, MTX2 KDM4E 4686/4885ALOX12 580/4885TDP1 4498/4885
US-20070015662-A1 Herbicide/safener combination CYP2W1, CBR3, DDT KDM4E 3689/4885ALOX12 1565/4885TDP1 708/4885
US-20040157739-A1 Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators CYP4Z1, IL4I1, BCAT1 KDM4E 743/4885ALOX12 2707/4885TDP1 2791/4885
US-10301257-B2 Use of acylsulfonamides for improving plant yield ARSA, ACSS2, NAT1 KDM4E 2044/4885ALOX12 946/4885TDP1 3841/4885
US-20150373975-A1 USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES SLC11A2, ERG28, CYTH3 KDM4E 3677/4885ALOX12 2339/4885TDP1 4595/4885
US-20040224848-A1 Herbicides comprising benzoylcyclohexanediones and safeners DDT, HPD, HDHD5 KDM4E 3009/4885ALOX12 663/4885TDP1 1227/4885
US-20050233906-A1 Oil suspension concentrate TST, PFAS, STS KDM4E 1810/4885ALOX12 102/4885TDP1 2053/4885
US-20060276342-A1 Herbicidal compositions DDT, HDHD5, DGAT2 KDM4E 639/4885ALOX12 917/4885TDP1 2025/4885
US-20150291518-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD ARSA, ACSS2, NAT1 KDM4E 2044/4885ALOX12 946/4885TDP1 3841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.