Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458203 | 0.89 | NR1H4 (0.55) | NPSR1MAPTKDM4EGAAHSD17B10 | |
| SCHEMBL5316474 | 0.86 | GAA (0.49) | NPSR1MAPTKDM4EGAAHSD17B10 | |
| SCHEMBL1020649 | 0.80 | L3MBTL1 (0.68) | MAPTGAAL3MBTL1PLK1NR1H4 | |
| SCHEMBL8044311 | 0.78 | PLK1 (0.48) | NPSR1MAPTKDM4EGAAHSD17B10 | |
| SCHEMBL6926831 | 0.78 | PLK1 (0.51) | NPSR1MAPTKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL25385448 | 0.77 | PLK1 (0.50) | NPSR1MAPTKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL25384637 | 0.76 | PLK1 (0.49) | MAPTKDM4EHSD17B10L3MBTL1PLK1 | |
| SCHEMBL1021042 | 0.76 | PLK1 (0.67) | GAAL3MBTL1PLK1MAPK14NR1H4 | |
| SCHEMBL1353027 | 0.76 | PTGS2 (0.49) | MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL5316479 | 0.75 | NPC1 (0.54) | NPSR1MAPTKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225753-A1 | POTENT AND SELCTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS | Leukos Biotech, S.L. (ES) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022074103-A1 | POTENT AND SELCTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS | LEUKOS BIOTECH, S.L. (ES) | 2022-04-14 | — | — | WO | disclosed |