Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12486172 | 0.94 | ALDH1A1 (0.41) | FAAHCNR1CNR2LMNACA1 | |
| SCHEMBL11068862 | 0.91 | LMNA (0.55) | FAAHCNR1CNR2LMNAALDH1A1 | |
| SCHEMBL21711304 | 0.91 | LMNA (0.55) | FAAHCNR1CNR2LMNAALDH1A1 | |
| SCHEMBL8761882 | 0.91 | LMNA (0.55) | FAAHCNR1CNR2LMNAALDH1A1 | |
| SCHEMBL28226286 | 0.89 | LMNA (0.52) | FAAHCNR1CNR2LMNAALDH1A1 | |
| SCHEMBL7954263 | 0.86 | FFAR4 (0.49) | FAAHCNR1CNR2ALDH1A1GPR84 | |
| SCHEMBL7945815 | 0.86 | FFAR4 (0.49) | FAAHCNR1CNR2ALDH1A1GPR84 | |
| SCHEMBL7954272 | 0.86 | FFAR4 (0.49) | FAAHCNR1CNR2ALDH1A1GPR84 | |
| SCHEMBL7954243 | 0.86 | FFAR4 (0.49) | FAAHCNR1CNR2ALDH1A1GPR84 | |
| SCHEMBL7954840 | 0.86 | FFAR4 (0.49) | FAAHCNR1CNR2ALDH1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167024-A2 | COOLING COMPOUNDS | Givaudan SA (CH) | 2010-03-31 | — | — | EP | claimed |
| WO-2008151460-A2 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2008-12-18 | — | — | WO | claimed |
| EP-2167024-A2 | COOLING COMPOUNDS | Givaudan SA (CH) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008151460-A2 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2008-12-18 | — | — | WO | disclosed |