SCHEMBL29459690

SCHEMBL29459690

COc1cc(OC)c2ccccc2c1C=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.44
ALDH1A1 P00352 3/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP1A2 P05177 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
PADI4 Q9UM07 1/20 0.42
IMPDH2 P12268 1/20 0.42
IMPDH1 P20839 1/20 0.42
IDO1 P14902 1/20 0.41
MCL1 Q07820 1/20 0.41
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
EP300 Q09472 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
TTR P02766 1/20 0.40
SLC2A1 P11166 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1004872 1.00 ERN1 (0.44) ERN1ALDH1A1TSHRTDP1KDM4E
SCHEMBL9839130 0.87 MAPT (0.44) ERN1ALDH1A1TSHRTDP1KDM4E
SCHEMBL5950414 0.85 ALDH1A1 (0.50) ERN1ALDH1A1TSHRTDP1KDM4E
SCHEMBL10897941 0.84 ERN1 (0.41) ERN1ALDH1A1TSHRTDP1CYP1A2
SCHEMBL13243654 0.84 IDO1 (0.50) ERN1ALDH1A1TSHRTDP1CYP1A2
SCHEMBL1002684 0.84 ERN1 (0.53) ERN1ALDH1A1TSHRTDP1MAPT
SCHEMBL29708049 0.84 ERN1 (0.53) ERN1ALDH1A1TSHRTDP1MAPT
SCHEMBL20562170 0.79 ALDH1A1 (0.49) ERN1ALDH1A1TSHRCYP1A2MAPT
SCHEMBL4257992 0.79 ALOX15 (0.43) KDM4ECYP1A2MAPTCYP2C9CYP2C19
SCHEMBL11306283 0.78 MAPT (0.45) ERN1ALDH1A1TSHRTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
EP-4003286-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-06-01 EP claimed
CN-114173750-A Improving the stability of agents for treating keratin materials 汉高股份有限及两合公司 2022-03-11 CN claimed
EP-4291951-A1 TWO-COMPONENT SYSTEM Xetos AG (DE) 2023-12-20 EP disclosed
CN-116830040-A Photopolymerizable compositions 西托斯股份公司 2023-09-29 CN disclosed
EP-4043961-B1 2K SYSTEM XETOS AG (DE) 2023-08-16 EP disclosed
WO-2022233824-A1 NAPHTHALENE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER INSTITUT CURIE (FR) 2022-11-10 WO disclosed
WO-2022171823-A1 PHOTOPOLYMERIZABLE COMPOSITION XETOS AG (DE) 2022-08-18 WO disclosed
WO-2022171814-A1 TWO-COMPONENT SYSTEM XETOS AG (DE) 2022-08-18 WO disclosed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN disclosed
EP-4003286-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-06-01 EP disclosed
CN-114173750-A Improving the stability of agents for treating keratin materials 汉高股份有限及两合公司 2022-03-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO ERN1 4459/4885ALDH1A1 111/4885TSHR 3526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.