SCHEMBL29460474

SCHEMBL29460474

C[C@H](N)C(=O)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.67
▸ MEN1 O00255 1/20 0.67
▸ ABL1 P00519 1/20 0.67
▸ LMNA P02545 1/20 0.67
▸ PKM P14618 1/20 0.67
▸ IDE P14735 1/20 0.67
▸ MAPK1 P28482 1/20 0.67
▸ KMT2A Q03164 1/20 0.67
▸ RIN1 Q13671 1/20 0.67
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ HLCS P50747 6/20 0.60
▸ CA12 O43570 7/20 0.54
▸ CA1 P00915 7/20 0.54
▸ CA2 P00918 7/20 0.54
▸ CA9 Q16790 7/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30058455 0.86 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL30094823 0.85 HLCS (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL31364275 0.84 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
SCHEMBL29462121 0.84 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
SCHEMBL29460477 0.84 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL23011940 0.84 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL13253736 0.84 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL12060572 0.84 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL12116013 0.84 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL13253967 0.84 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139075-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS INC (US) 2026-05-21 — — US disclosed
US-12559573-B2 Biotin-specific monoclonal antibody and use thereof ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2026-02-24 — — US disclosed
US-20250306016-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS INC (US) 2025-10-02 — — US disclosed
US-20220107309-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS GMBH (DE) 2022-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250306016-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF BTD, IGLV6-57, VSIR TDP1 4750/4885MEN1 3221/4885ABL1 3134/4885
US-20220107309-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF BTD, IGLV6-57, VSIR TDP1 4750/4885MEN1 3221/4885ABL1 3134/4885
US-12559573-B2 Biotin-specific monoclonal antibody and use thereof IGLV6-57, LY96, BTD TDP1 4725/4885MEN1 2651/4885ABL1 1952/4885
US-20260139075-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF CD22, LY96, F13B TDP1 4799/4885MEN1 1057/4885ABL1 2440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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