SCHEMBL29462121

SCHEMBL29462121

NCCCC[C@H](N)C(=O)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.62
▸ MEN1 O00255 1/20 0.61
▸ ABL1 P00519 1/20 0.61
▸ LMNA P02545 1/20 0.61
▸ PKM P14618 1/20 0.61
▸ IDE P14735 1/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ RIN1 Q13671 1/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ HLCS P50747 6/20 0.54
▸ CA12 O43570 7/20 0.51
▸ CA1 P00915 7/20 0.51
▸ CA2 P00918 7/20 0.51
▸ CA9 Q16790 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30094823 0.90 HLCS (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL2536441 0.89 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
SCHEMBL31364275 0.89 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
Hydrochloric Acid SCHEMBL3417755 0.88 TDP1 (0.61) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3790437 0.87 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL693036 0.87 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
SCHEMBL30058455 0.86 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL1033634 0.85 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
SCHEMBL28346778 0.85 TDP1 (0.61) TDP1MEN1ABL1LMNAPKM
SCHEMBL29460477 0.85 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117706083-A Chemiluminescent immunoassay kit, preparation method and detection method thereof 深圳市卓润生物科技有限公司 2024-03-15 — — CN claimed
CN-113105526-B Polypeptide, application thereof, probe comprising polypeptide and kit 北京鲲达宇科技有限公司 2022-04-26 — — CN claimed
EP-4745152-A2 PEPTIDES BINDING TO BFL-1 Dana-Farber Cancer Institute, Inc. (US) 2026-05-20 — — EP disclosed
EP-3341008-B1 PEPTIDES BINDING TO BFL-1 DANA FARBER CANCER INST INC (US) 2026-04-15 — — EP disclosed
US-12570698-B2 Stabilized peptides for covalent binding to target protein DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-03-10 — — US disclosed
US-12552873-B2 Anti-PSGL-1 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof VERSEAU THERAPEUTICS, INC. (US) 2026-02-17 — — US disclosed
EP-4661892-A1 TNF-ALPHA BINDING AGENTS AND METHODS OF USING THE SAME Navigen, Inc. (US) 2025-12-17 — — EP disclosed
US-12466853-B2 Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive NOXA peptides DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-11-11 — — US disclosed
US-RE50594-E1 Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-09-23 — — US disclosed
US-12398179-B2 Nanomolar peptides and derivatives to differentially modulate ephrin receptors Sanford Burnham Prebys Medical Discovery Institute (US) 2025-08-26 — — US disclosed
WO-2025151826-A1 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS WITH METADATA TAGGING ABRUS BIO, INC. (US) 2025-07-17 — — WO disclosed
WO-2023028603-A2 ENGINEERED COMPOSITIONS HUMABS BIOMED SA (CH) 2023-03-02 — — WO disclosed
US-20220396632-A1 ANTI-PSGL-1 COMPOSITIONS AND METHODS FOR MODULATING MYELOID CELL INFALMMATORY PHENOTYPES AND USES THEREOF VERSEAU THERAPEUTICS, INC. 2022-12-15 — — US disclosed
CN-113024640-B Epitope peptide antigen detection neutralizing antibody kit based on screening of binding domain of RBD and ACE2 receptor of new coronavirus 广州中医药大学顺德医院(佛山市顺德区中医院) 2022-07-26 — — CN disclosed
US-20220213146-A1 STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN DANA-FARBER CANCER INSTITUTE, INC. 2022-07-07 — — US disclosed
WO-2022115486-A1 ANTIBODIES THAT BIND TO MULTIPLE BETACORONAVIRUSES Vir Biotechnology, Inc. (US) 2022-06-02 — — WO disclosed
US-20220144893-A1 NANOMOLAR PEPTIDES AND DERIVATIVES TO DIFFERENTIALLY MODULATE EPHRIN RECEPTORS Sanford Burnham Prebys Medical Discovery Institute 2022-05-12 — — US disclosed
CN-113388025-B Polypeptide, composition and application thereof 北京鲲达宇科技有限公司 2022-04-29 — — CN disclosed
CN-113105526-B Polypeptide, application thereof, probe comprising polypeptide and kit 北京鲲达宇科技有限公司 2022-04-26 — — CN disclosed
WO-2022056473-A1 COMPOSITIONS AND METHODS FOR TREATING DISEASES Sanford Burnham Prebys Medical Discovery Institute (US) 2022-03-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466853-B2 Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive NOXA peptides MCL1, BCL2L1, BCL2L11 TDP1 220/4885MEN1 1146/4885ABL1 1015/4885
US-12570698-B2 Stabilized peptides for covalent binding to target protein STUB1, JMJD7, PTMS TDP1 3504/4885MEN1 3215/4885ABL1 2191/4885
US-20220213146-A1 STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN HSPBP1, HSPA8, PTMS TDP1 3688/4885MEN1 2924/4885ABL1 2230/4885
US-12552873-B2 Anti-PSGL-1 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof CD209, CSF3R, CHI3L1 TDP1 3965/4885MEN1 3559/4885ABL1 2068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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