Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 18/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009852 | 0.72 | RIPK1 (0.74) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL31064987 | 0.71 | RIPK1 (1.00) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL31064965 | 0.71 | RIPK1 (1.00) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL2997190 | 0.71 | RIPK1 (1.00) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL13543890 | 0.70 | RIPK1 (0.58) | RIPK1DAO | |
| SCHEMBL29460546 | 0.69 | RIPK1 (0.65) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL2995238 | 0.69 | RIPK1 (0.73) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL3006162 | 0.69 | RIPK1 (0.73) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL12606336 | 0.69 | RIPK1 (0.56) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL21117175 | 0.69 | RIPK1 (0.48) | RIPK1CCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149428-A | Pyridine-fused ring compound and preparation method, intermediate, composition and application thereof | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |