Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785083 | 0.94 | ECE1 (0.43) | PDCD1LG2CD274ECE1ALDH1A1LMNA | |
| SCHEMBL29351498 | 0.90 | ALDH1A1 (0.47) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29379914 | 0.88 | PTGS1 (0.50) | PDCD1LG2CD274ECE1ALDH1A1LMNA | |
| SCHEMBL7575574 | 0.88 | GLO1 (0.44) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29744873 | 0.87 | PDCD1LG2 (0.44) | PDCD1LG2CD274ECE1ALDH1A1LMNA | |
| SCHEMBL30116702 | 0.87 | PTGS1 (0.40) | PDCD1LG2CD274ECE1MMP8PTGS1 | |
| SCHEMBL30099477 | 0.87 | ECE1 (0.40) | PDCD1LG2CD274ECE1ALDH1A1LMNA | |
| SCHEMBL29644351 | 0.87 | PDCD1LG2 (0.44) | PDCD1LG2CD274ECE1ALDH1A1LMNA | |
| SCHEMBL7575589 | 0.86 | GLO1 (0.44) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL31187794 | 0.84 | ECE1 (0.51) | PDCD1LG2CD274ECE1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220105190-A1 | METHODS OF USING GLYCOPOLYSIALYLATED THERAPEUTIC PROTEINS | LIPOXEN TECHNOLOGIES LIMITED (US) | 2022-04-07 | — | — | US | disclosed |