Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460686 | 0.94 | PDCD1LG2 (0.41) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29379914 | 0.93 | PTGS1 (0.50) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL7575574 | 0.93 | GLO1 (0.44) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL30099477 | 0.93 | ECE1 (0.40) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL7575589 | 0.92 | GLO1 (0.44) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29410682 | 0.89 | ALDH1A1 (0.47) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL17283446 | 0.89 | ALDH1A1 (0.47) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL8128334 | 0.86 | PTGS1 (0.43) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL8071951 | 0.86 | PTGS1 (0.43) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL6902897 | 0.86 | PTGS1 (0.43) | ECE1ALDH1A1LMNAMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521504-B | Anti-human EGFR nano antibody and application thereof | 暨南大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-112457404-B | Anti-human EGFR nano antibody and application | 暨南大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-112457405-B | Anti-human EGFR nano antibody and application | 暨南大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-112552402-B | Anti-human EGFR nano antibody and application | 暨南大学 | 2022-08-12 | — | — | CN | disclosed |