Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22308557 | 1.00 | NR1I2 (0.40) | NR1I2FAAHCYP2D6CYP3A4NAAA | |
| SCHEMBL18947485 | 0.93 | CYP2D6 (0.41) | NR1I2FAAHCYP2D6CYP3A4NAAA | |
| SCHEMBL21362944 | 0.93 | CYP2D6 (0.41) | NR1I2FAAHCYP2D6CYP3A4NAAA | |
| SCHEMBL19890344 | 0.93 | CYP2D6 (0.41) | NR1I2FAAHCYP2D6CYP3A4NAAA | |
| SCHEMBL26774452 | 0.93 | CYP2D6 (0.41) | NR1I2FAAHCYP2D6CYP3A4NPC1 | |
| SCHEMBL20052787 | 0.93 | CYP2D6 (0.41) | NR1I2FAAHCYP2D6CYP3A4NAAA | |
| SCHEMBL18638711 | 0.92 | FAAH (0.40) | NR1I2FAAHCYP2D6CYP3A4NAAA | |
| SCHEMBL19225133 | 0.92 | FAAH (0.40) | NR1I2FAAHCYP2D6CYP3A4NAAA | |
| SCHEMBL21362869 | 0.92 | CYP2D6 (0.41) | NR1I2FAAHCYP2D6CYP3A4NAAA | |
| SCHEMBL25771267 | 0.90 | CYP2D6 (0.41) | NR1I2FAAHCYP2D6CYP3A4NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | CURASEN THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | ADRA1A, ADRB1, ADRA1D | NR1I2 253/4885FAAH 564/4885CYP2D6 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.