Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606799 | 0.70 | BRPF1 (0.51) | BRPF1PRKCIKDM4ECHEK1AURKA | |
| SCHEMBL12825045 | 0.69 | BRPF1 (0.50) | BRPF1PRKCIKDM4ECHEK1AURKA | |
| SCHEMBL6969376 | 0.69 | HSD17B10 (0.66) | BRPF1PRKCIKDM4ECHEK1AURKA | |
| SCHEMBL31036167 | 0.69 | BRPF1 (0.62) | BRPF1PRKCIKDM4EALDH1A1MAPT | |
| SCHEMBL3481207 | 0.69 | BRPF1 (0.62) | BRPF1PRKCIKDM4EALDH1A1MAPT | |
| SCHEMBL21638907 | 0.68 | IDO1 (0.47) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL28083587 | 0.68 | BRPF1 (0.49) | BRPF1PRKCIKDM4ECHEK1AURKA | |
| SCHEMBL28281962 | 0.67 | BRPF1 (0.56) | BRPF1PRKCIKDM4ECHEK1AURKA | |
| Hydrochloric Acid SCHEMBL27614396 | 0.67 | BRPF1 (0.61) | BRPF1PRKCIKDM4ERAD52ALDH1A1 | |
| SCHEMBL1173839 | 0.66 | MAPT (0.52) | BRPF1KDM4ELMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12465588-B2 | Indole carboxamide derivative and pharmaceutical composition containing same | KUKJE PHARMA CO., LTD. (KR) | 2025-11-11 | — | — | US | disclosed |
| CN-114302874-B | Indole carboxamide derivatives and pharmaceutical compositions containing the same | 国际药品株式会社 | 2025-02-25 | — | — | CN | disclosed |
| US-20230000821-A1 | INDOLE CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KUKJE PHARMA CO., LTD. (KR) | 2023-01-05 | — | — | US | disclosed |
| EP-4023638-A1 | INDOLE CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Kukje Pharma Co., Ltd. (KR) | 2022-07-06 | — | — | EP | disclosed |
| CN-114302874-A | Indole carboxamide derivatives and pharmaceutical compositions comprising same | 国际药品株式会社 | 2022-04-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12465588-B2 | Indole carboxamide derivative and pharmaceutical composition containing same | PTGES, PTGES2, PTGS1 | BRPF1 2787/4885PRKCI 2694/4885KDM4E 2460/4885 |
| US-20230000821-A1 | INDOLE CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | PTGES, PTGES2, PTGS1 | BRPF1 2787/4885PRKCI 2694/4885KDM4E 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.