SCHEMBL29463333

SCHEMBL29463333

CCC(C)C(NC(=O)C1CCCN1C(=O)C(Cc1cnc[nH]1)NC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)CNC)C(C)C)C(C)CC)C(=O)O

nearest known ligand 0.89

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 6/20 0.89
AGTR1 P30556 5/20 0.89
NTSR1 P30989 3/20 0.64
NTSR2 O95665 1/20 0.64
REN P00797 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29720225 0.97 AGTR2 (0.84) AGTR2AGTR1NTSR1NTSR2REN
Acetic Acid SCHEMBL34470176 0.94 AGTR2 (0.83) AGTR2AGTR1NTSR1NTSR2REN
Saralasin SCHEMBL24 0.93 AGTR1 (0.82) AGTR2AGTR1
Saralasin SCHEMBL1650804 0.92 AGTR1 (0.80) AGTR2AGTR1
SCHEMBL29486803 0.90 AGTR2 (0.76) AGTR2AGTR1REN
SCHEMBL29599255 0.89 AGTR2 (0.90) AGTR2AGTR1NTSR1NTSR2REN
SCHEMBL29382642 0.88 AGTR2 (0.78) AGTR2AGTR1NTSR1NTSR2REN
Angiotensin-Ii SCHEMBL34470359 0.88 AGTR2 (0.90) AGTR2AGTR1
Trv-120027 SCHEMBL29382211 0.88 AGTR1 (0.73) AGTR2AGTR1
SCHEMBL31332289 0.87 AGTR2 (0.91) AGTR2AGTR1NTSR1NTSR2REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159467-A1 NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2023-05-25 US disclosed
EP-4121165-A1 NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-01-25 EP disclosed
US-20220244254-A1 Screening Methods and Assays for Use with Transmembrane Proteins, in Particular with GPCRs CONFO THERAPEUTICS N.V. (BE) 2022-08-04 US disclosed
EP-3963329-A1 SCREENING METHODS AND ASSAYS FOR USE WITH TRANSMEMBRANE PROTEINS, IN PARTICULAR WITH GPCRS Confo Therapeutics N.V. (BE) 2022-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159467-A1 NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II AGTR2, AGTR1, AGT AGTR2 1/4885AGTR1 2/4885NTSR1 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.