SCHEMBL29599255

SCHEMBL29599255

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.90

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 7/20 0.90
AGTR1 P30556 4/20 0.90
REN P00797 2/20 0.66
NTSR2 O95665 1/20 0.66
NTSR1 P30989 1/20 0.66
LNPEP Q9UIQ6 3/20 0.65
ANPEP P15144 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31332289 0.95 AGTR2 (0.91) AGTR2AGTR1RENNTSR2NTSR1
SCHEMBL29619824 0.95 AGTR2 (0.94) AGTR2AGTR1
Angiotensin Ii SCHEMBL29361852 0.95 AGTR2 (1.00) AGTR2AGTR1
Angiotensin Ii SCHEMBL21811603 0.95 AGTR2 (1.00) AGTR2AGTR1
Angiotensin Ii SCHEMBL1650427 0.95 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL29394721 0.95 AGTR2 (1.00) AGTR2AGTR1
Angiotensin Ii SCHEMBL31477824 0.94 AGTR2 (0.98) AGTR2AGTR1
SCHEMBL29382642 0.93 AGTR2 (0.78) AGTR2AGTR1RENNTSR2NTSR1
Acetic Acid SCHEMBL34470176 0.93 AGTR2 (0.83) AGTR2AGTR1RENNTSR2NTSR1
SCHEMBL28485749 0.92 AGTR2 (0.94) AGTR2AGTR1NTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090251-A1 METHODS FOR IMPROVING TREATMENT OUTCOMES IN PATIENTS UNDERGOING ULTRAFILTRATION PROLETARIAT THERAPEUTICS, INC. (US) 2026-04-30 WO claimed
US-20240426840-A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATMENT OF MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS TEXAS A & M UNIV SYS (US) 2024-12-26 US claimed
WO-2026090251-A1 METHODS FOR IMPROVING TREATMENT OUTCOMES IN PATIENTS UNDERGOING ULTRAFILTRATION PROLETARIAT THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-20260053430-A1 VOICE-BASED MONITORING AND ALERTING FOR REMOTE DECOMPENSATED HEART FAILURE DETECTION NOAH LABS GMBH (DE) 2026-02-26 US disclosed
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) UNIV LELAND STANFORD JUNIOR (US) 2026-02-19 US disclosed
US-20250347677-A1 BIOLOGICAL NANOPORES HAVING TUNABLE PORE DIAMETERS AND USES THEREOF AS ANALYTICAL TOOLS UNIV GRONINGEN (NL) 2025-11-13 US disclosed
US-20250223580-A1 PROGRAMMABLE NUCLEASE-PEPTIDASE COMPOSITIONS THE BROAD INSTITUTE, INC. 2025-07-10 US disclosed
US-12336840-B2 Voice-based monitoring and alerting for remote decompensated heart failure detection NOAH LABS GMBH (DE) 2025-06-24 US disclosed
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2025-06-05 US disclosed
WO-2025046236-A1 METHODS FOR NANOPORE-BASED ANALYTE DETECTION PORTAL BIOTECH LIMITED (GB) 2025-03-06 WO disclosed
US-20250000445-A1 VOICE ANALYSIS TO PREDICT DECOMPENSATED HEART FAILURE NOAH LABS GMBH (DE) 2025-01-02 US disclosed
US-12060397-B2 Soluble lipidated ligand agents for treating eye inflammation TUFTS MEDICAL CENTER (US) 2024-08-13 US disclosed
CN-116981697-A Secreted payload modulation 森迪生物科学公司 2023-10-31 CN disclosed
US-20230165790-A1 NASAL FOAM VIA CRIBRIFORM PLATE FOR MEDICATION DELIVERY TO THE BRAIN AND/OR BODY AND FOR NASAL MOISTURIZATION AND HYGIENE GUPTA SANJAY (US) 2023-06-01 US disclosed
CN-112225713-B Synthesis process of 5-hydroxybenzofuran compound 华东理工大学 2023-02-28 CN disclosed
CN-111024960-B Additive for detecting hypertension blood sample, kit and application 广州阳普医疗科技股份有限公司 2023-02-17 CN disclosed
US-11576857-B2 Nasal foam via cribriform plate for medication delivery to the brain and/or body and for nasal moisturization and hygiene GUPTA SANJAY (US) 2023-02-14 US disclosed
US-11559483-B2 Nasal foam via cribriform plate for medication delivery to the brain and/or body and for nasal moisturization and hygiene GUPTA SANJAY (US) 2023-01-24 US disclosed
CN-114514032-A Angiotensin type 2 (AT2) receptor agonists for the treatment of cancer 兰提欧派普有限公司 2022-05-17 CN disclosed
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2022-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG AGTR2 1051/4885AGTR1 1339/4885REN 3060/4885
US-20260053430-A1 VOICE-BASED MONITORING AND ALERTING FOR REMOTE DECOMPENSATED HEART FAILURE DETECTION NPPA, NPR1, NPR3 AGTR2 336/4885AGTR1 427/4885REN 570/4885
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) ADAR, ZFR, SLIRP AGTR2 3417/4885AGTR1 3360/4885REN 4833/4885
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG AGTR2 1051/4885AGTR1 1339/4885REN 3060/4885
US-12060397-B2 Soluble lipidated ligand agents for treating eye inflammation LIPG, CD40, LDLR AGTR2 601/4885AGTR1 850/4885REN 2001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.