Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29888963 | 0.87 | MMP3 (0.44) | CAPN1PSMB9RENKMT2AMMP3 | |
| SCHEMBL30468684 | 0.86 | APLNR (0.43) | CAPN1PSMB9RENKMT2AMMP3 | |
| SCHEMBL15095228 | 0.84 | KMT2A (0.45) | CAPN1PSMB9RENCTSBKMT2A | |
| SCHEMBL10646770 | 0.84 | KMT2A (0.53) | CAPN1PSMB9CTSBKMT2A | |
| SCHEMBL10646776 | 0.84 | KMT2A (0.53) | CAPN1PSMB9CTSBKMT2A | |
| SCHEMBL30483724 | 0.83 | REN (0.44) | CAPN1PSMB9RENKMT2AMMP3 | |
| SCHEMBL29407478 | 0.83 | REN (0.44) | CAPN1PSMB9RENKMT2AMMP3 | |
| SCHEMBL29699495 | 0.83 | KMT2A (0.43) | CAPN1PSMB9RENCTSBKMT2A | |
| SCHEMBL8751425 | 0.82 | KMT2A (0.49) | PSMB9CTSBKMT2AAPLNR | |
| SCHEMBL10525117 | 0.82 | KMT2A (0.59) | CAPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3964242-B1 | SURGICAL STAPLER WITH END EFFECTOR COATING | CILAG GMBH INT (CH) | 2026-02-18 | — | — | EP | disclosed |
| US-11992216-B2 | Surgical stapler with end effector coating | CILAG GMBH INTERNATIONAL (CH) | 2024-05-28 | — | — | US | disclosed |
| US-11666335-B2 | Surgical stapler with end effector coating | CILAG GMBH INTERNATIONAL (CH) | 2023-06-06 | — | — | US | disclosed |
| US-20230071644-A1 | SURGICAL STAPLER WITH END EFFECTOR COATING | ETHICON LLC (US) | 2023-03-09 | — | — | US | disclosed |
| CN-111032104-B | Surgical stapler with end effector coating | 爱惜康有限责任公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-110740763-B | Surgical fastener device for preventing degradation of ECM | 爱惜康有限责任公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110769866-B | Surgical stapler with controlled healing | 爱惜康有限责任公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-110740764-B | Surgical fasteners with broad spectrum MMP inhibitors | 爱惜康有限责任公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-3964242-A1 | SURGICAL STAPLER WITH END EFFECTOR COATING | Cilag GmbH International (CH) | 2022-03-09 | — | — | EP | disclosed |