Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.50 |
| ▸ | P4HB | P07237 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | UNG | P13051 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67236 | 1.00 | FBP1 (0.56) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| Cyclopropane SCHEMBL29130088 | 0.94 | FBP1 (0.51) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18002842 | 0.92 | FBP1 (0.58) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| Ethylene Glycol SCHEMBL28844357 | 0.91 | FBP1 (0.53) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| Propionaldehyde SCHEMBL28092395 | 0.89 | PDCD1 (0.49) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8704159 | 0.89 | ALDH1A1 (0.69) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15821011 | 0.88 | TRIM24 (0.49) | FBP1ALDH1A1MAOB | |
| SCHEMBL9190941 | 0.87 | FBP1 (0.57) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6153715 | 0.84 | SRC (0.46) | FBP1P4HBALDH1A1MAOAMAOB | |
| SCHEMBL28265256 | 0.83 | FBP1 (0.53) | FBP1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024124287-A1 | COMPOUNDS FOR TREATING VIRAL INFECTION | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2024-06-20 | — | — | WO | disclosed |
| EP-4370578-A1 | ACCELERATOR FOR EPOXY RESINS | Sika Technology AG (CH) | 2024-05-22 | — | — | EP | disclosed |
| EP-4237086-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2023285188-A1 | ACCELERATOR FOR EPOXY RESINS | SIKA TECHNOLOGY AG (CH) | 2023-01-19 | — | — | WO | disclosed |
| EP-4003985-A1 | MODULATORS OF TREX1 | Constellation Pharmaceuticals, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| WO-2022093856-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-05-05 | — | — | WO | disclosed |
| EP-3962481-A1 | KCNT1 INHIBITORS AND METHODS OF USE | Praxis Precision Medicines, Inc. (US) | 2022-03-09 | — | — | EP | disclosed |