SCHEMBL67236

SCHEMBL67236

N#Cc1cccc(C=O)c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 3/20 0.56
GRIN2D O15399 2/20 0.50
GRIN3B O60391 2/20 0.50
GRIN1 Q05586 2/20 0.50
GRIN2A Q12879 2/20 0.50
GRIN2B Q13224 2/20 0.50
GRIN2C Q14957 2/20 0.50
GRIN3A Q8TCU5 2/20 0.50
P4HB P07237 8/20 0.49
ALDH1A1 P00352 1/20 0.48
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
FFAR1 O14842 1/20 0.44
UNG P13051 1/20 0.44
ENPP2 Q13822 1/20 0.44
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29463498 1.00 FBP1 (0.56) FBP1GRIN2DGRIN3BGRIN1GRIN2A
Cyclopropane SCHEMBL29130088 0.94 FBP1 (0.51) FBP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL18002842 0.92 FBP1 (0.58) FBP1GRIN2DGRIN3BGRIN1GRIN2A
Ethylene Glycol SCHEMBL28844357 0.91 FBP1 (0.53) FBP1GRIN2DGRIN3BGRIN1GRIN2A
Propionaldehyde SCHEMBL28092395 0.89 PDCD1 (0.49) FBP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8704159 0.89 ALDH1A1 (0.69) FBP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15821011 0.88 TRIM24 (0.49) FBP1ALDH1A1MAOB
SCHEMBL9190941 0.87 FBP1 (0.57) FBP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6153715 0.84 SRC (0.46) FBP1P4HBALDH1A1MAOAMAOB
SCHEMBL28265256 0.83 FBP1 (0.53) FBP1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3353 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899184-A Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease 中国人民解放军北部战区总医院 2025-04-29 CN claimed
CN-115141120-B Electro-oxidation preparation method of atta Lu Lun 湖南大学 2025-03-21 CN claimed
CN-118852032-A Alpha, beta-unsaturated ketone derivative, preparation method and application thereof 赣南医科大学 2024-10-29 CN claimed
CN-118561718-A Combined production process of 3-cyanobenzaldehyde and isophthalonitrile 上海凌凯科技股份有限公司 2024-08-30 CN claimed
CN-115160300-B Coumarin compound, preparation method thereof and application of coumarin compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2024-05-31 CN claimed
CN-117902959-A Alkyl functionalized hexa-arene used for stationary phase, preparation method thereof, capillary gas chromatographic column and application thereof 沈阳工业大学 2024-04-19 CN claimed
CN-116283821-B Phencyclized propylamine compound, preparation method and application 郑州大学 2024-01-26 CN claimed
CN-117362162-A Preparation method of carbonyl compound 中国科学院大连化学物理研究所 2024-01-09 CN claimed
CN-114713206-B Preparation and application of imidazole ionic liquid functionalized star-type block polymer stationary phase 沈阳工业大学 2023-11-14 CN claimed
CN-116283821-A Phencyclized propylamine compound, preparation method and application 郑州大学 2023-06-23 CN claimed
WO-1998034115-A1 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
EP-0539153-B1 Acridine derivative as therapeutic agent ZENECA LTD (GB) 1997-04-23 EP claimed
CN-1146202-A Quinolone derivative for treatment of urinary incontinence ZENECA LTD (GB) 1997-03-26 CN claimed
EP-0755382-A1 QUINOLONE DERIVATIVE FOR TREATMENT OF URINARY INCONTINENCE ZENECA LIMITED (GB) 1997-01-29 EP claimed
WO-1995028388-A1 QUINOLONE DERIVATIVE FOR TREATMENT OF URINARY INCONTINENCE ZENECA LIMITED (GB) 1995-10-26 WO claimed
EP-0539153-A1 Acridine derivative as therapeutic agent ZENECA LIMITED (GB) 1993-04-28 EP claimed
US-5049551-A Antitumor UBE INDUSTRIES, LTD. (JP) 1991-09-17 US claimed
EP-0400610-A1 5-Fluorouracil derivatives UBE INDUSTRIES, LTD. (JP) 1990-12-05 EP claimed
US-4143068-A PROCESS FOR THE PREPARATION OF ACYL CYANIDE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1979-03-06 US claimed
US-3951993-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed