Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 3/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925087 | 1.00 | HSD11B1 (0.35) | HSD11B1MPLSCN1ASCN8ASCN9A | |
| SCHEMBL29464850 | 0.90 | SCN1A (0.38) | HSD11B1SCN1ASCN8ASCN5A | |
| SCHEMBL19925692 | 0.90 | SCN1A (0.38) | HSD11B1SCN1ASCN8ASCN5A | |
| SCHEMBL19927703 | 0.88 | HSD11B1 (0.37) | HSD11B1MPLSCN9ASLC40A1SLC22A12 | |
| SCHEMBL29464412 | 0.88 | HSD11B1 (0.37) | HSD11B1MPLSCN9ASLC40A1SLC22A12 | |
| SCHEMBL19928762 | 0.86 | HSD11B1 (0.38) | HSD11B1SCN1ASCN8ASCN9ASCN5A | |
| SCHEMBL29464516 | 0.86 | HSD11B1 (0.38) | HSD11B1SCN1ASCN8ASCN9ASCN5A | |
| SCHEMBL19968760 | 0.86 | PTPN1 (0.37) | HSD11B1MPLSCN9ASLC40A1SLC22A12 | |
| SCHEMBL29464335 | 0.86 | PTPN1 (0.37) | HSD11B1MPLSCN9ASLC40A1SLC22A12 | |
| SCHEMBL19925226 | 0.84 | PKM (0.36) | HSD11B1MPLSCN1ASCN8ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |