Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925151 | 1.00 | L3MBTL1 (0.40) | L3MBTL1HTTSLC22A12PIK3CDHSD11B1 | |
| SCHEMBL29464507 | 0.93 | L3MBTL1 (0.43) | L3MBTL1HTTSLC22A12PIK3CDHSD11B1 | |
| SCHEMBL19927806 | 0.93 | L3MBTL1 (0.43) | L3MBTL1HTTSLC22A12PIK3CDHSD11B1 | |
| SCHEMBL29464534 | 0.84 | PIK3CD (0.40) | L3MBTL1HTTPIK3CDHSD11B1ALDH1A1 | |
| SCHEMBL19925031 | 0.84 | PIK3CD (0.40) | L3MBTL1HTTPIK3CDHSD11B1ALDH1A1 | |
| SCHEMBL29464474 | 0.83 | HSD11B1 (0.36) | L3MBTL1PIK3CDHSD11B1ALDH1A1PIK3CA | |
| SCHEMBL19925085 | 0.83 | HSD11B1 (0.36) | L3MBTL1PIK3CDHSD11B1ALDH1A1PIK3CA | |
| SCHEMBL29464429 | 0.81 | PIK3CD (0.46) | SLC22A12PIK3CDALDH1A1SCN9A | |
| SCHEMBL19968773 | 0.81 | PIK3CD (0.46) | SLC22A12PIK3CDALDH1A1SCN9A | |
| SCHEMBL29464524 | 0.81 | PIK3CD (0.46) | SLC22A12PIK3CDALDH1A1PIK3CASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |