Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 5/20 | 0.32 |
| ▸ | TYK2 | P29597 | 5/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.31 |
| ▸ | KHK | P50053 | 2/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951407 | 1.00 | SOS1 (0.39) | SOS1ARKIF18ASCN9AJAK2 | |
| SCHEMBL29464448 | 0.89 | KIF18A (0.36) | SOS1KIF18ASCN9A | |
| SCHEMBL19925682 | 0.89 | KIF18A (0.36) | SOS1KIF18ASCN9A | |
| SCHEMBL19925028 | 0.88 | SOS1 (0.36) | SOS1ARKIF18AJAK2TYK2 | |
| SCHEMBL19951298 | 0.86 | KIF18A (0.34) | SOS1ARKIF18ASLC22A12KHK | |
| SCHEMBL29464339 | 0.86 | KIF18A (0.34) | SOS1ARKIF18ASLC22A12KHK | |
| SCHEMBL19968848 | 0.84 | KIF18A (0.37) | SOS1KIF18ASCN9A | |
| SCHEMBL19925208 | 0.82 | KIF18A (0.36) | SOS1KIF18ASCN9A | |
| SCHEMBL19925199 | 0.82 | KIF18A (0.36) | SOS1KIF18ASCN9A | |
| SCHEMBL23770564 | 0.82 | SOS1 (0.40) | SOS1ARJAK2TYK2KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |