Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 8/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951369 | 1.00 | KIF18A (0.35) | KIF18ADGAT1KCNH2CNR1SMYD2 | |
| SCHEMBL19951367 | 1.00 | KIF18A (0.35) | KIF18ADGAT1KCNH2CNR1SMYD2 | |
| SCHEMBL19925396 | 0.89 | KIF18A (0.33) | KIF18ADGAT1KCNH2KMOJAK2 | |
| SCHEMBL19925398 | 0.89 | KIF18A (0.33) | KIF18ADGAT1KCNH2KMOJAK2 | |
| SCHEMBL29464342 | 0.89 | KIF18A (0.33) | KIF18ADGAT1KCNH2KMOJAK2 | |
| SCHEMBL19927751 | 0.89 | CHRNA7 (0.37) | KIF18ADGAT1KCNH2CNR1HSD11B1 | |
| SCHEMBL29464332 | 0.89 | CHRNA7 (0.37) | KIF18ADGAT1KCNH2CNR1HSD11B1 | |
| SCHEMBL19927754 | 0.89 | CHRNA7 (0.37) | KIF18ADGAT1KCNH2CNR1HSD11B1 | |
| SCHEMBL19951305 | 0.87 | DGAT1 (0.34) | KIF18ADGAT1KCNH2KMOJAK2 | |
| SCHEMBL19951306 | 0.87 | DGAT1 (0.34) | KIF18ADGAT1KCNH2KMOJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |