Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18917430 | 1.00 | GAPDH (0.39) | GAPDHLMNAALDH1A1MAPTMAOB | |
| SCHEMBL18917435 | 0.85 | STAT3 (0.47) | GAPDHLMNAALDH1A1MAPTMAOB | |
| SCHEMBL29467148 | 0.85 | STAT3 (0.47) | GAPDHLMNAALDH1A1MAPTMAOB | |
| SCHEMBL27928192 | 0.79 | FGFR2 (0.38) | LMNAALDH1A1MAPTFGFR1STAT3 | |
| SCHEMBL18917429 | 0.78 | BACE1 (0.45) | LMNAALDH1A1MAPTBACE1ADORA2A | |
| SCHEMBL27810235 | 0.74 | STAT3 (0.35) | LMNAMAPTPDGFRBSTAT3STAT1 | |
| SCHEMBL18917432 | 0.71 | TOP1 (0.51) | LMNAALDH1A1MAPTADORA2AACHE | |
| SCHEMBL31300179 | 0.70 | GRIN1 (0.33) | MAOBSTAT3STAT1PKM | |
| SCHEMBL30561563 | 0.69 | STAT3 (0.38) | MAPTSTAT3STAT1 | |
| SCHEMBL28247692 | 0.69 | STAT3 (0.38) | MAPTSTAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779124-B | Gold porphyrin-PEG conjugates and methods of use | 香港大学 | 2022-03-01 | — | — | CN | disclosed |