SCHEMBL29467141 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	MAOB	P27338	2/20	0.42

▸	EGLN1	Q9GZT9	1/20	0.41

▸	MAPT	P10636	2/20	0.41

▸	HTT	P42858	1/20	0.41

▸	L3MBTL1	Q9Y468	1/20	0.41

▸	NR4A2	P43354	1/20	0.40

▸	KMT2A	Q03164	3/20	0.40

▸	MEN1	O00255	2/20	0.40

▸	SCD	O00767	3/20	0.40

▸	GPR52	Q9Y2T5	2/20	0.40

▸	ACP3	P15309	1/20	0.39

▸	CCR1	P32246	1/20	0.39

▸	TDP1	Q9NUW8	1/20	0.39

▸	ATM	Q13315	1/20	0.39

▸	TACR1	P25103	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28716139	1.00	MAOB (0.42)	MAOBEGLN1MAPTHTTL3MBTL1
SCHEMBL29467175	0.86	GPR119 (0.42)	MAOBL3MBTL1SCD
SCHEMBL28707994	0.86	GPR119 (0.42)	MAOBL3MBTL1SCD
SCHEMBL28714232	0.84	KDM1A (0.43)	MAOBEGLN1MAPTSCD
SCHEMBL29467161	0.84	KDM1A (0.43)	MAOBEGLN1MAPTSCD
SCHEMBL28719227	0.83	SCD (0.43)	MAPTKMT2ASCD
SCHEMBL29467187	0.83	SCD (0.43)	MAPTKMT2ASCD
SCHEMBL29467160	0.83	ATM (0.47)	MAOBKMT2AMEN1GPR52ACP3
SCHEMBL20029212	0.82	SCD (0.47)	SCD
SCHEMBL28707297	0.81	ALKBH1 (0.41)	SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114206861-A	Fused heteroaryl compounds useful as RIPK1 inhibitors	比西切姆有限公司	2022-03-18	—	—	CN	disclosed