Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGAV | P06756 | 3/20 | 0.47 |
| ▸ | KYNU | Q16719 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29336444 | 0.94 | LMNA (0.54) | LMNASMN1; SMN2FOLH1SIRT2SIRT1 | |
| SCHEMBL15382100 | 0.90 | LMNA (0.57) | LMNASMN1; SMN2FOLH1SIRT2SIRT1 | |
| SCHEMBL23537876 | 0.89 | LMNA (0.49) | LMNASMN1; SMN2FOLH1SIRT2SIRT1 | |
| SCHEMBL29467688 | 0.89 | LMNA (0.49) | LMNASMN1; SMN2SIRT2SIRT1CAPN1 | |
| SCHEMBL29467617 | 0.88 | LMNA (0.47) | LMNASMN1; SMN2SIRT2SIRT1CAPN1 | |
| SCHEMBL23451317 | 0.85 | SIRT2 (0.58) | FOLH1SIRT2SIRT1ITGB3ITGAV | |
| SCHEMBL25333001 | 0.85 | SIRT2 (0.58) | FOLH1SIRT2SIRT1ITGB3ITGAV | |
| SCHEMBL23451316 | 0.85 | SIRT2 (0.58) | FOLH1SIRT2SIRT1ITGB3ITGAV | |
| SCHEMBL25332996 | 0.85 | SIRT2 (0.58) | FOLH1SIRT2SIRT1ITGB3ITGAV | |
| SCHEMBL13324010 | 0.85 | SIRT2 (0.61) | FOLH1SIRT2SIRT1CAPN1CAPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426727-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | Hangzhou Dac Biotech Co., Ltd. (CN) | 2024-09-11 | — | — | EP | disclosed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| EP-3986463-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2022-04-27 | — | — | EP | disclosed |
| WO-2022078524-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |