Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 3/20 | 0.30 |
| ▸ | PKLR | P30613 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24334439 | 1.00 | ACLY (0.39) | ACLYHTR1AHTR4CHRM1CHRM2 | |
| SCHEMBL24333714 | 0.90 | ACLY (0.40) | ACLYHTR1AHTR4CHRM1CHRM2 | |
| SCHEMBL24333798 | 0.87 | PKLR (0.30) | PKLR | |
| SCHEMBL24334286 | 0.81 | F2 (0.32) | HTR1AALDH1A1TSHRPKM | |
| SCHEMBL29469635 | 0.81 | F2 (0.32) | HTR1AALDH1A1TSHRPKM | |
| SCHEMBL29469655 | 0.81 | CA12 (0.31) | CHRM1CHRM2KCNH2MCHR1 | |
| SCHEMBL24333606 | 0.81 | CA12 (0.31) | CHRM1CHRM2KCNH2MCHR1 | |
| SCHEMBL24334433 | 0.81 | HTR1A (0.33) | HTR1AADORA2AADORA1NPC1TP53 | |
| SCHEMBL24333793 | 0.79 | PKLR (0.34) | ALDH1A1TSHRTP53RAB9ASMN1; SMN2 | |
| SCHEMBL24333584 | 0.79 | POLB (0.40) | ALDH1A1TSHRTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | claimed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | claimed |
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |