Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732065 | 0.83 | HSD11B1 (0.55) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL14177658 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRSIGMAR1LMNAGAA | |
| SCHEMBL107297 | 0.75 | CYP3A4 (0.55) | ALDH1A1TSHRGAAHSD17B10KMT2A | |
| SCHEMBL2942193 | 0.74 | TSHR (0.58) | ALDH1A1TSHRSIGMAR1LMNAKMT2A | |
| SCHEMBL6733710 | 0.74 | HSD11B1 (0.57) | ALDH1A1KMT2ACYP2D6MEN1 | |
| SCHEMBL7442356 | 0.73 | L3MBTL1 (0.49) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4522790 | 0.73 | L3MBTL1 (0.43) | ALDH1A1TSHRSIGMAR1LMNAKMT2A | |
| SCHEMBL14177723 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRGAAHSD17B10DYRK1A | |
| SCHEMBL14177722 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRGAAHSD17B10DYRK1A | |
| SCHEMBL14177626 | 0.72 | MAPT (0.51) | ALDH1A1SIGMAR1GAACMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754719-B2 | Substituted piperidine derivatives as somatostatin SST1 receptor antagonists | NOVARTIS AG (CH) | 2010-07-13 | — | — | US | disclosed |
| EP-1909792-B1 | SUBSTITUTED PIPERIDINE DERIVATIVES AS SOMATOSTATIN SST1 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080255142-A1 | Substituted Piperidine Derivatives as Somatostatin Sst1 Receptor Antagonists | NOVARTIS AG (CH) | 2008-10-16 | — | — | US | disclosed |
| EP-1909792-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES AS SOMATOSTATIN SST1 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007009662-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES AS SOMATOSTATIN SST1 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255142-A1 | Substituted Piperidine Derivatives as Somatostatin Sst1 Receptor Antagonists | SSTR1, SSTR2, SSTR3 | ALDH1A1 2021/4885TSHR 24/4885SIGMAR1 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.