Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692866 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRGLAALDH1A1POLB | |
| SCHEMBL29469796 | 0.81 | CA1 (0.47) | SMN1; SMN2TSHRALDH1A1POLBMAPT | |
| SCHEMBL29469841 | 0.81 | CA1 (0.47) | SMN1; SMN2TSHRALDH1A1POLBMAPT | |
| SCHEMBL1137871 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRGLAALDH1A1LMNA | |
| Methane SCHEMBL25341724 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRGLAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL27865616 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRGLAALDH1A1LMNA | |
| SCHEMBL22588315 | 0.79 | CA1 (0.53) | SMN1; SMN2ALDH1A1POLBHTTPKM | |
| SCHEMBL27381455 | 0.77 | CA2 (0.41) | SMN1; SMN2TSHRGLAALDH1A1LMNA | |
| SCHEMBL22588191 | 0.77 | ALDH1A1 (0.62) | SMN1; SMN2TSHRGLAALDH1A1POLB | |
| SCHEMBL9259271 | 0.76 | MAPK1 (0.58) | SMN1; SMN2TSHRALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |