SCHEMBL29470184

SCHEMBL29470184

C[C@H](NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 3/20 0.68
▸ ECE1 P42892 12/20 0.63
▸ ERAP2 Q6P179 1/20 0.60
▸ ALOX15 P16050 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21641793 0.96 ACE (0.73) ACEECE1ERAP2ALOX15
SCHEMBL21641791 0.96 ACE (0.73) ACEECE1ERAP2ALOX15
SCHEMBL29380886 0.96 ACE (0.73) ACEECE1ERAP2ALOX15
SCHEMBL21641792 0.96 ACE (0.73) ACEECE1ERAP2ALOX15
SCHEMBL30051858 0.93 ACE (0.69) ACEECE1ALOX15
SCHEMBL30465920 0.92 ACE (0.64) ACEECE1
SCHEMBL29750422 0.91 ACE (0.67) ACEECE1ERAP2ALOX15
SCHEMBL3497589 0.90 ACE (0.72) ACEECE1ALOX15
SCHEMBL30051627 0.90 ACE (0.72) ACEECE1ALOX15
SCHEMBL30123268 0.90 ACE (0.66) ACEECE1ERAP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12449422-B2 Method and composition matter for immunoproteasome-mediated delivery into living cells PURDUE RESEARCH FOUNDATION (US) 2025-10-21 — — US disclosed
US-20220120756-A1 METHOD AND COMPOSITION MATTER FOR IMMUNOPROTEASOME-MEDIATED DELIVERY INTO LIVING CELLS PURDUE RESEARCH FOUNDATION (US) 2022-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220120756-A1 METHOD AND COMPOSITION MATTER FOR IMMUNOPROTEASOME-MEDIATED DELIVERY INTO LIVING CELLS EXOSC5, PSMG3, EXOSC4 ACE 563/4885ECE1 1178/4885ERAP2 105/4885
US-12449422-B2 Method and composition matter for immunoproteasome-mediated delivery into living cells EXOSC5, PSMG3, EXOSC4 ACE 563/4885ECE1 1178/4885ERAP2 105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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