SCHEMBL29470193

SCHEMBL29470193

C[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.59
▸ ECE1 P42892 12/20 0.56
▸ ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31571737 0.95 GHSR (0.59) ACEECE1
SCHEMBL11497997 0.94 ACE (0.60) ACEECE1ALOX15
SCHEMBL7046020 0.94 ACE (0.60) ACEECE1ALOX15
SCHEMBL7046017 0.94 ACE (0.60) ACEECE1ALOX15
Hydrochloric Acid SCHEMBL7702115 0.94 ACE (0.59) ACEECE1ALOX15
SCHEMBL31259938 0.92 ACE (0.57) ACEECE1ALOX15
SCHEMBL30628987 0.92 ACE (0.57) ACEECE1ALOX15
SCHEMBL31259940 0.92 ACE (0.57) ACEECE1ALOX15
SCHEMBL29973876 0.92 ACE (0.57) ACEECE1ALOX15
SCHEMBL30628999 0.92 ACE (0.57) ACEECE1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12449422-B2 Method and composition matter for immunoproteasome-mediated delivery into living cells PURDUE RESEARCH FOUNDATION (US) 2025-10-21 — — US disclosed
US-20220120756-A1 METHOD AND COMPOSITION MATTER FOR IMMUNOPROTEASOME-MEDIATED DELIVERY INTO LIVING CELLS PURDUE RESEARCH FOUNDATION (US) 2022-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220120756-A1 METHOD AND COMPOSITION MATTER FOR IMMUNOPROTEASOME-MEDIATED DELIVERY INTO LIVING CELLS EXOSC5, PSMG3, EXOSC4 ACE 563/4885ECE1 1178/4885ALOX15 1516/4885
US-12449422-B2 Method and composition matter for immunoproteasome-mediated delivery into living cells EXOSC5, PSMG3, EXOSC4 ACE 563/4885ECE1 1178/4885ALOX15 1516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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