SCHEMBL294704

SCHEMBL294704

C=CC(=O)NCN1CCOCC1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.46
RAB9A P51151 1/20 0.45
MAPK1 P28482 2/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HIF1A Q16665 1/20 0.43
KDM4E B2RXH2 3/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
GAA P10253 1/20 0.39
GLA P06280 1/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 2/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6853288 0.82 ALDH1A1 (0.48) MEN1KMT2AMAPK1TSHRALDH1A1
SCHEMBL793119 0.82 MEN1 (0.57) MEN1KMT2ARAB9AMAPK1TSHR
SCHEMBL2058650 0.81 ALDH1A1 (0.46) MEN1KMT2ASMN1; SMN2MAPK1TSHR
Hydrochloric Acid SCHEMBL31228331 0.81 ALDH1A1 (0.46) MEN1KMT2AMAPK1TSHRALDH1A1
SCHEMBL610613 0.80 MAPK1 (0.68) MEN1KMT2ASMN1; SMN2RAB9AMAPK1
SCHEMBL11045712 0.79 TSHR (0.48) MEN1KMT2AMAPK1TSHRALDH1A1
SCHEMBL10714041 0.78 MAPK1 (0.62) MEN1KMT2ASMN1; SMN2RAB9AMAPK1
SCHEMBL2733785 0.78 ALDH1A1 (0.43) MEN1KMT2AMAPK1TSHRALDH1A1
SCHEMBL17650808 0.77 RAB9A (0.56) MEN1KMT2ASMN1; SMN2RAB9AMAPK1
SCHEMBL28719503 0.77 MEN1 (0.52) MEN1KMT2ARAB9AMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421872-B1 Stain resistant coating composition THE SHERWIN-WILLIAMS COMPANY (US) 2019-09-24 US claimed
US-9938424-B2 Coating compositions for improved block resistance ARKEMA INC. (US) 2018-04-10 US claimed
US-9724288-B2 Copolymers useful as rheology modifiers and home and personal care compositions comprising said copolymers BASF SE (DE) 2017-08-08 US claimed
US-20170009095-A1 COATING COMPOSITIONS FOR IMPROVED BLOCK RESISTANCE ARKEMA INC (US) 2017-01-12 US claimed
US-20160338939-A1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS COMPRISING SAID COPOLYMERS BASF SE (DE) 2016-11-24 US claimed
EP-2328547-B1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS BASF SE (DE) 2014-03-05 EP claimed
EP-2039343-B1 Cosmetic compositions containing a cationic copolymer and a particular amino silicone and uses thereof OREAL (FR) 2012-12-05 EP claimed
EP-2328547-A1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS BASF SE (DE) 2011-06-08 EP claimed
WO-2010026097-A1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS BASF SE (DE) 2010-03-11 WO claimed
US-20100056647-A1 Copolymers useful as rheology modifiers and home and personal care compositions comprising said copolymers CIBA CORPORATION (US) 2010-03-04 US claimed
EP-2039346-A1 Cosmetic composition comprising a cationic copolymer and a starch and cosmetic treatment process L'Oréal (FR) 2009-03-25 EP claimed
EP-2039343-A1 Cosmetic compositions containing a cationic copolymer and a particular amino silicone and uses thereof L'Oréal (FR) 2009-03-25 EP claimed
US-20090074696-A1 COSMETIC COMPOSITION COMPRISING A CATIONIC COPOLYMER AND A STARCH AND COSMETIC TREATMENT PROCESS THEREOF L'OREAL S.A. (FR) 2009-03-19 US claimed
EP-2036590-A2 Cosmetic compositions containing a cationic copolymer, a cyclodextrin and a surfactant, and uses thereof L'Oréal (FR) 2009-03-18 EP claimed
EP-1018535-B1 Solvent-free vinyl acetate-ethylene compositions comprising an acrylic polymer CELANESE INT CORP (US) 2005-12-07 EP claimed
EP-0710680-B1 Aqueous polymer dispersion BASF AG (DE) 2003-03-19 EP claimed
CN-1280594-A Scrub resistant latexes UNION CARBIDE CHEM PLASTIC (US) 2001-01-17 CN claimed
CN-1052014-C Waterborne core-shell latex polymers MINNESOTA MINING & MFG (US) 2000-05-03 CN claimed
EP-0609756-A2 Latex paint formulations containing no organic solvents based on multistage polymers National Starch and Chemical Investment Holding Corporation (US) 1994-08-10 EP claimed
US-3957492-A Photographic silver halide emulsion comprising an amphoteric copolymer FUJI PHOTO FILM CO., LTD. (JA) 1976-05-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074696-A1 COSMETIC COMPOSITION COMPRISING A CATIONIC COPOLYMER AND A STARCH AND COSMETIC TREATMENT PROCESS THEREOF TYR, OXGR1, OGFOD1 MEN1 4432/4885KMT2A 3868/4885SMN1; SMN2 3404/4885
US-20160338939-A1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS COMPRISING SAID COPOLYMERS PHLPP1, PHLPP2, F12 MEN1 546/4885KMT2A 1481/4885SMN1; SMN2 2819/4885
US-20100056647-A1 Copolymers useful as rheology modifiers and home and personal care compositions comprising said copolymers PHLPP1, PHLPP2, F12 MEN1 546/4885KMT2A 1481/4885SMN1; SMN2 2819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.