Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.67 |
| ▸ | CES1 | P23141 | 3/20 | 0.67 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192962 | 1.00 | CES2 (0.67) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL4957103 | 0.82 | ALDH1A1 (0.54) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL3026551 | 0.82 | KCNQ3 (0.51) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL193605 | 0.82 | KCNQ3 (0.51) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL11669995 | 0.82 | ALDH1A1 (0.54) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL18707178 | 0.82 | KDM4E (0.53) | CES2CES1POLB | |
| SCHEMBL13012035 | 0.80 | CES2 (0.43) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL789006 | 0.80 | CES2 (0.43) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL925050 | 0.80 | HDAC1 (0.61) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL146573 | 0.80 | NPC1 (0.46) | CES2CES1RAB9AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624140-A | CXCR4 antagonists, methods of making and uses thereof | 杭州师范大学 | 2024-03-01 | — | — | CN | claimed |
| CN-113307768-B | Quinolone derivative and preparation method and application thereof | 中国农业科学院兰州畜牧与兽药研究所 | 2023-12-12 | — | — | CN | claimed |
| CN-112752837-B | Natural killer cells | 帝国理工学院创新有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-122010767-A | Haloalkyl bisamide compound and application thereof | 山东熙霖生物科技有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-20250206753-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | ABBVIE INC. | 2025-06-26 | — | — | US | disclosed |
| CN-120040420-A | Heterocyclic-pyrazole amine derivatives, preparation method thereof and application thereof in resisting tubercle bacillus infection | 中国医学科学院医药生物技术研究所 | 2025-05-27 | — | — | CN | disclosed |
| CN-119684287-A | 4- (3- (Piperidin-4-yl) -1H-pyrazol-5-yl) -1H-pyrrole [2,3-b ] pyridine derivative, and preparation method and application thereof | 烟台新药创制山东省实验室 | 2025-03-25 | — | — | CN | disclosed |
| CN-119528777-A | Sulfonated monomer and preparation method thereof, polymer and proton exchange membrane | 华为技术有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119060061-A | Application of benzopyrimidine thioether compounds as STING protein small molecule inhibitors | 浙江师范大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-119039255-A | 5-Hydroxy-3-methylfuran-2 (5H) -one derivative, preparation method and application thereof | 安徽农业大学 | 2024-11-29 | — | — | CN | disclosed |
| WO-2024213044-A1 | AZACYCLO-CARBONYL-FUSED RING DERIVATIVES AND USE THEREOF | Beijing Double-Crane Runchuang Technology Co., Ltd. (CN) | 2024-10-17 | — | — | WO | disclosed |
| CN-116478134-A | SSRI/5-HT 1A Double-target antidepressant formylpiperidine compound and preparation method and application thereof | 上海医药工业研究院有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-114014824-B | Application of heterocyclic compound | 上海科技大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-115819417-A | Pyrazolopyridine derivatives as HPK1 modulators and their use for the treatment of cancer | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115385902-A | Benzimidazole compound and preparation method and application thereof | 徐州医科大学 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022246392-A1 | CYCLIC AMIDE-CONTAINING PYRIDYL XANTHINES AS A 2B ANTAGONISTS | PURNOVATE, INC. (US) | 2022-11-24 | — | — | WO | disclosed |
| CN-109923114-B | Pyrazolopyridine derivatives as HPK1 modulators and their use for the treatment of cancer | 因赛特公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114380762-A | Isoxazoline hydrazide derivative and preparation method and application thereof | 贵州大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-114014824-A | Application of heterocyclic compound | 上海科技大学 | 2022-02-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206753-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | VHL, BRDT, PAICS | CES2 816/4885CES1 1353/4885KCNQ3 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.