SCHEMBL193605

SCHEMBL193605

O=C(Cl)c1ccc(F)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNQ3 O43525 1/20 0.51
KCNQ2 O43526 1/20 0.51
KCNE1 P15382 1/20 0.51
KCNQ1 P51787 1/20 0.51
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SLC2A1 P11166 1/20 0.46
TAS1R3 Q7RTX0 3/20 0.45
TAS1R1 Q7RTX1 3/20 0.45
TAS1R2 Q8TE23 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 1/20 0.45
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
MDM2 Q00987 1/20 0.44
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3170407 0.84 CES2 (0.64) KCNQ3KCNQ2KCNE1KCNQ1NPC1
SCHEMBL10399614 0.84 SRD5A2 (0.53) KCNQ3KCNQ2KCNE1KCNQ1NPC1
SCHEMBL20084007 0.83 KCNQ3 (0.47) KCNQ3KCNQ2KCNE1KCNQ1NPC1
SCHEMBL3026551 0.83 KCNQ3 (0.51) KCNQ3KCNQ2KCNE1KCNQ1SLC2A1
SCHEMBL109599 0.83 TSHR (0.65) KCNQ3KCNQ2KCNE1KCNQ1NPC1
SCHEMBL9693915 0.83 KCNQ3 (0.47) KCNQ3KCNQ2KCNE1KCNQ1NPC1
SCHEMBL30308290 0.83 TSHR (0.65) KCNQ3KCNQ2KCNE1KCNQ1NPC1
SCHEMBL192962 0.82 CES2 (0.67) KCNQ3KCNQ2KCNE1KCNQ1NPC1
SCHEMBL29470947 0.82 CES2 (0.67) KCNQ3KCNQ2KCNE1KCNQ1NPC1
SCHEMBL6024105 0.81 KCNQ3 (0.46) KCNQ3KCNQ2KCNE1KCNQ1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117727940-A Lithium iron manganese phosphate positive electrode material and preparation method thereof 湖南蒙星纳米材料科技有限公司 2024-03-19 CN claimed
EP-0922693-B1 Process for the preparation of 3-chloro-4-fluorobenzoyl chloride CLARIANT GMBH (DE) 2001-10-24 EP claimed
US-6187952-B1 Two-step production of 3-chloro-4-fluoro-benzoyl chloride by chlorination CLARIANT GMBH (DE) 2001-02-13 US claimed
EP-0922693-A1 Process for the preparation of 3-chloro-4-fluorobenzoyl chloride Clariant GmbH (DE) 1999-06-16 EP claimed
JP-11236346-A None JP disclosed
JP-11158111-A None JP disclosed
CN-121872907-A Method for co-producing 3-chloro-4-fluorobenzoyl chloride and 3, 5-dichloro-4-fluorobenzoyl chloride 湖北联昌新材料有限公司 2026-04-17 CN disclosed
CN-121872907-A Method for co-producing 3-chloro-4-fluorobenzoyl chloride and 3, 5-dichloro-4-fluorobenzoyl chloride 湖北联昌新材料有限公司 2026-04-17 CN disclosed
CN-120040420-A Heterocyclic-pyrazole amine derivatives, preparation method thereof and application thereof in resisting tubercle bacillus infection 中国医学科学院医药生物技术研究所 2025-05-27 CN disclosed
US-12208110-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-01-28 US disclosed
US-20240228501-A1 IMIDAZOLE-CONTAINING CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US disclosed
US-11963967-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-04-23 US disclosed
CN-1046835-A Go out and remove the method for rice insect pest ROHM & HAAS (US) 1990-11-14 CN disclosed
US-4704483-A FLUORINATION WITH POTASSIUM FLUORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1987-11-03 US disclosed
US-4582948-A VAPOR PHASE CHLORO-DENITRATION REACTION OCCIDENTAL CHEMICAL CORPORATION (US) 1986-04-15 US disclosed
US-RE32087-E 4H-3,1-Benzoxazine derivatives BASF AKTIENGESELLSCHAFT (DE) 1986-02-25 US disclosed
EP-0159388-A2 Preparation of nuclear chlorinated compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1985-10-30 EP disclosed
US-4470930-A Preparation of nuclear chlorinated aromatic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1984-09-11 US disclosed
US-4315766-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US disclosed
EP-0017931-A2 4H-3,1-Benzoxazine derivatives, methods of their preparation and their use in combating undesirable vegetation BASF Aktiengesellschaft (DE) 1980-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12208110-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS1, SGMS2 KCNQ3 1804/4885KCNQ2 1655/4885KCNE1 1758/4885
US-11963967-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 KCNQ3 2522/4885KCNQ2 2350/4885KCNE1 3017/4885
US-20240228501-A1 IMIDAZOLE-CONTAINING CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE KISS1R, CYP3A43, SLC6A11 KCNQ3 62/4885KCNQ2 337/4885KCNE1 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.