Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25299970 | 1.00 | DPP4 (0.42) | DPP4CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL27838509 | 0.82 | DPP4 (0.42) | DPP4ALDH1A1S100A4CDC25BKCNA5 | |
| SCHEMBL12854150 | 0.78 | ALDH1A1 (0.50) | DPP4ALDH1A1S100A4CDC25BPTPRC | |
| SCHEMBL23585490 | 0.75 | ADRA1A (0.44) | DPP4S100A4CDC25BPTPRCCTSL | |
| SCHEMBL18483362 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KMT2ATRPA1GRM5MEN1 | |
| SCHEMBL30021329 | 0.74 | PTGS2 (0.53) | DPP4ALDH1A1KCNA5PTPRCCTSL | |
| SCHEMBL17826981 | 0.74 | DPP4 (0.71) | DPP4CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL18448568 | 0.73 | ALOX5AP (0.41) | DPP4ALDH1A1TRPA1GRM5 | |
| SCHEMBL29471016 | 0.73 | ALOX5AP (0.41) | DPP4ALDH1A1TRPA1GRM5 | |
| SCHEMBL805420 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669733-A | Polymorphic forms of rorgamma inhibiting compounds and methods of making the same | 格兰马克专业公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4208449-A1 | POLYMORPHIC FORMS OF A RORGAMMA INHIBITING COMPOUND AND PROCESSES FOR ITS PREPARATION | Glenmark Specialty S.A. (CH) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022049534-A1 | POLYMORPHIC FORMS OF A RORΓ INHIBITING COMPOUND AND PROCESSES FOR ITS PREPARATION | GLENMARK SPECIALTY S.A. (CH) | 2022-03-10 | — | — | WO | disclosed |