Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.60 |
| ▸ | CTSK | P43235 | 6/20 | 0.60 |
| ▸ | CTSD | P07339 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612215 | 0.91 | CTSD (0.61) | CTSSCTSKCTSDCTSLCTSB | |
| SCHEMBL19944788 | 0.91 | CTSS (0.64) | CTSSCTSKCTSDCA2CTSL | |
| SCHEMBL29472202 | 0.89 | CTSD (0.55) | CTSSCTSKCTSDCTSLCTSB | |
| SCHEMBL29472194 | 0.88 | CTSS (0.54) | CTSSCTSKCTSDCA2REN | |
| SCHEMBL11365513 | 0.88 | CTSS (0.68) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL31181953 | 0.88 | CTSS (0.77) | CTSSCTSKCTSLCTSB | |
| SCHEMBL31181954 | 0.87 | CTSS (0.52) | CTSSCTSKCTSDCA2CTSL | |
| SCHEMBL4018237 | 0.87 | CTSS (0.66) | CTSSCTSKCTSLCTSB | |
| SCHEMBL11683746 | 0.87 | CTSS (0.66) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4018243 | 0.87 | CTSS (0.66) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353546-B | Preparation and application of oligopeptide modified bisindolylethyl-beta-carboline-3-carboxylic acid | 首都医科大学 | 2024-10-08 | — | — | CN | disclosed |
| CN-112010937-B | YIGSR modified pentacyclic piperazinedione and preparation and application thereof | 首都医科大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115353546-A | Preparation and application of oligopeptide-modified bis-indolylethyl-beta-carboline-3-carboxylic acid | 首都医科大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-109134605-B | 1, 1-dihydroxymethyl-tetrahydro-beta-carboline-3-formyl-GYIGSK, and synthesis, activity and application thereof | 首都医科大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-109134603-B | 1, 1-dihydroxymethyl-tetrahydro-beta-carboline-3-formyl-GYIGSR, and synthesis, activity and application thereof | 首都医科大学 | 2022-04-22 | — | — | CN | disclosed |