Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279132 | 1.00 | PDE2A (0.60) | PDE2AAKR1C3AKR1C2HTR2ARAB9A | |
| SCHEMBL13698776 | 0.86 | PDE2A (0.46) | PDE2AAKR1C3AKR1C2HTR2ARAB9A | |
| SCHEMBL17763832 | 0.83 | PDE2A (0.44) | PDE2AAKR1C3AKR1C2HTR2ARAB9A | |
| SCHEMBL18103190 | 0.83 | PDE2A (0.44) | PDE2AAKR1C3AKR1C2HTR2ARAB9A | |
| SCHEMBL29472452 | 0.83 | PDE2A (0.44) | PDE2AAKR1C3AKR1C2HTR2ARAB9A | |
| Hydrochloric Acid SCHEMBL31137630 | 0.79 | HTR2A (0.50) | PDE2AHTR2ARAB9AL3MBTL1KCNH2 | |
| Hydrochloric Acid SCHEMBL31136523 | 0.79 | HTR2A (0.50) | PDE2AHTR2ARAB9AL3MBTL1KCNH2 | |
| SCHEMBL18075239 | 0.78 | PDE2A (0.68) | PDE2AHTR2ALIPG | |
| SCHEMBL30481795 | 0.78 | PDE2A (0.68) | PDE2AHTR2ALIPG | |
| SCHEMBL19898274 | 0.77 | PDE2A (0.66) | PDE2AHTR2ALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220098159-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098159-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | CASP1, IL1B, PYCARD | PDE2A 900/4885AKR1C3 463/4885AKR1C2 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.