SCHEMBL29474205

SCHEMBL29474205

Nc1ccc2sc3ccccc3c2c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.77
ALDH1A1 P00352 6/20 0.77
RAB9A P51151 4/20 0.77
SMN1; SMN2 Q16637 3/20 0.77
HPGD P15428 3/20 0.77
GPR3 P46089 1/20 0.61
KDM4E B2RXH2 4/20 0.44
NPC1 O15118 3/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
CYP1A2 P05177 1/20 0.44
PARP1 P09874 1/20 0.43
PTPN7 P35236 1/20 0.41
DUSP3 P51452 1/20 0.41
PTPN12 Q05209 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
POLB P06746 1/20 0.41
APP P05067 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5110289 1.00 MAPT (0.77) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL18359685 0.89 ALDH1A1 (0.81) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL3887754 0.89 MAPT (0.58) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL30340804 0.89 MAPT (0.58) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL14174144 0.88 MAPT (0.92) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL2343867 0.87 ALDH1A1 (1.00) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL29671010 0.87 ALDH1A1 (1.00) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL29671009 0.87 ALDH1A1 (1.00) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL3480951 0.84 MAPT (0.73) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL31238914 0.84 MAPT (0.73) MAPTALDH1A1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240260453-A1 Organic Light-Emitting Compound And Organic Light-Emitting Device Comprising Same P&H TECH CO., LTD (KR) 2024-08-01 US disclosed
CN-117820304-A Organic material composition and application thereof 宁波卢米蓝新材料有限公司 2024-04-05 CN disclosed
CN-116925057-A High-thermal stability hole transport material based on dibenzothiophene end group and synthesis method thereof 南京理工大学 2023-10-24 CN disclosed
CN-116925057-A High-thermal stability hole transport material based on dibenzothiophene end group and synthesis method thereof 南京理工大学 2023-10-24 CN disclosed
CN-116354834-A Hole transport compound and organic light emitting device including the same 贝匹科有限公司 2023-06-30 CN disclosed
CN-110997650-B Compound for organic electric element, organic electric element using same, and electronic device using same 德山新勒克斯有限公司 2023-05-09 CN disclosed
WO-2022240172-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME (주)피엔에이치테크 2022-11-17 WO disclosed
WO-2022210821-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2022-10-06 WO disclosed
CN-109476626-B Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2022-09-09 CN disclosed
CN-114788030-A Organic electroluminescent element comprising organic compound, electronic device comprising the same 德山新勒克斯有限公司 2022-07-22 CN disclosed
CN-114207861-A Organic electronic device 德山新勒克斯有限公司 2022-03-18 CN disclosed
CN-114207859-A Organic electronic device 德山新勒克斯有限公司 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240260453-A1 Organic Light-Emitting Compound And Organic Light-Emitting Device Comprising Same DDT, TYR, DBF4 MAPT 651/4885ALDH1A1 561/4885RAB9A 4259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.