Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 7/20 | 0.60 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.60 |
| ▸ | CHRNG | P07510 | 3/20 | 0.60 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.60 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952781 | 0.90 | CHRND (0.55) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL7586744 | 0.90 | CHRND (0.55) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL29630576 | 0.86 | OPRD1 (0.55) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL4629789 | 0.84 | NAALAD2 (0.59) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL10824355 | 0.84 | NAALAD2 (0.59) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL30100565 | 0.83 | OPRD1 (0.73) | — | |
| SCHEMBL38659045 | 0.82 | CHRND (0.59) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL24122752 | 0.82 | CHRND (0.56) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL7866090 | 0.82 | CHRND (0.56) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL7866097 | 0.82 | CHRND (0.56) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507353-A | Methods of treating melanocortin-4 receptor pathway-related disorders | 节奏制药公司 | 2023-07-28 | — | — | CN | disclosed |