SCHEMBL29477149

SCHEMBL29477149

O=C(O)Cc1c(Cl)[nH]c2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.66
ALDH1A1 P00352 3/20 0.66
GAA P10253 2/20 0.66
MAPT P10636 1/20 0.66
CASP1 P29466 1/20 0.66
CASP7 P55210 1/20 0.66
EGFR P00533 5/20 0.64
SRC P12931 2/20 0.49
NR4A2 P43354 1/20 0.47
AKR1B1 P15121 1/20 0.47
FOLH1 Q04609 1/20 0.46
GLA P06280 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4975424 1.00 KDM4E (0.66) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL7964387 0.85 KDM4E (0.53) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL28190374 0.81 EGFR (0.68) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL6824403 0.81 KDM4E (0.59) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL29470940 0.81 KDM4E (0.68) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL5211637 0.81 ALDH1A1 (0.68) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL4468686 0.81 KDM4E (0.68) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL152237 0.79 KDM4E (0.66) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL5063952 0.79 ALDH1A1 (0.66) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL379103 0.79 KDM4E (1.00) KDM4EALDH1A1GAAMAPTCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12507648-B2 Methods and compositions for rapid plant transformation PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-12-30 US disclosed
US-20250324934-A1 METHODS AND COMPOSITIONS FOR RAPID PLANT TRANSFORMATION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-10-23 US disclosed
CN-108368517-B Methods and compositions for rapid plant transformation 先锋国际良种公司 2022-08-02 CN disclosed
US-11330776-B2 Methods and compositions for rapid plant transformation PIONEER HI-BRED INTERNATIONAL, INC. 2022-05-17 US disclosed
US-20220124998-A1 METHODS AND COMPOSITIONS FOR RAPID PLANT TRANSFORMATION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507648-B2 Methods and compositions for rapid plant transformation POF1B, IWS1, CCNH KDM4E 4595/4885ALDH1A1 4180/4885GAA 3694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.