SCHEMBL4975424

SCHEMBL4975424

O=C(O)Cc1c(Cl)[nH]c2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.66
ALDH1A1 P00352 3/20 0.66
GAA P10253 2/20 0.66
MAPT P10636 1/20 0.66
CASP1 P29466 1/20 0.66
CASP7 P55210 1/20 0.66
EGFR P00533 5/20 0.64
SRC P12931 2/20 0.49
NR4A2 P43354 1/20 0.47
AKR1B1 P15121 1/20 0.47
FOLH1 Q04609 1/20 0.46
GLA P06280 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29477149 1.00 KDM4E (0.66) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL7964387 0.85 KDM4E (0.53) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL28190374 0.81 EGFR (0.68) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL6824403 0.81 KDM4E (0.59) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL29470940 0.81 KDM4E (0.68) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL5211637 0.81 ALDH1A1 (0.68) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL4468686 0.81 KDM4E (0.68) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL152237 0.79 KDM4E (0.66) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL5063952 0.79 ALDH1A1 (0.66) KDM4EALDH1A1GAAMAPTCASP1
SCHEMBL379103 0.79 KDM4E (1.00) KDM4EALDH1A1GAAMAPTCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107779494-A A kind of kit for detecting infective vaginitis and preparation method thereof 北京中生金域诊断技术股份有限公司 2018-03-09 CN claimed
US-12507648-B2 Methods and compositions for rapid plant transformation PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-12-30 US disclosed
US-20250324934-A1 METHODS AND COMPOSITIONS FOR RAPID PLANT TRANSFORMATION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-10-23 US disclosed
CN-114573496-B Preparation method of 4-chloroindole-3-acetic acid 贵州大学 2023-11-07 CN disclosed
CN-108368517-B Methods and compositions for rapid plant transformation 先锋国际良种公司 2022-08-02 CN disclosed
US-11330776-B2 Methods and compositions for rapid plant transformation PIONEER HI-BRED INTERNATIONAL, INC. 2022-05-17 US disclosed
US-20220124998-A1 METHODS AND COMPOSITIONS FOR RAPID PLANT TRANSFORMATION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2022-04-28 US disclosed
EP-3368676-B1 METHODS AND COMPOSITIONS FOR RAPID PLANT TRANSFORMATION PIONEER HI BRED INT (US) 2021-05-26 EP disclosed
EP-3368676-A1 METHODS AND COMPOSITIONS FOR RAPID PLANT TRANSFORMATION Pioneer Hi-Bred International, Inc. (US) 2018-09-05 EP disclosed
CN-108368517-A Method and composition for quick-speed plant conversion 先锋国际良种公司 2018-08-03 CN disclosed
CN-107779494-A A kind of kit for detecting infective vaginitis and preparation method thereof 北京中生金域诊断技术股份有限公司 2018-03-09 CN disclosed
US-20170325457-A1 FORMULATIONS FOR THE DELIVERY OF ACTIVE AGENTS TO INSECTS, PLANTS, AND PLANT PATHOGENS Preceres Inc. (US) 2017-11-16 US disclosed
WO-2017144065-A1 SUSTAINABLE AND INDUSTRIAL PRODUCTION OF GUAIANOLIDES BASED ON ORGAN TISSUE CULTURE UNIVERSITY OF COPENHAGEN (DK) 2017-08-31 WO disclosed
CN-107090486-A Product and method for detecting target microorganism 3M创新有限公司 2017-08-25 CN disclosed
WO-2017074547-A1 METHODS AND COMPOSITIONS FOR RAPID PLANT TRANSFORMATION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2017-05-04 WO disclosed
US-20170121722-A1 METHODS AND COMPOSITIONS FOR RAPID PLANT TRANSFORMATION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2017-05-04 US disclosed
CN-103621505-A Application of halogenated indole-3-acetic acid as herbicide UNIV SOUTHEAST 2014-03-12 CN disclosed
EP-1978805-A1 PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2008-10-15 EP disclosed
WO-2007085660-A1 PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2007-08-02 WO disclosed
US-20040040054-A1 Plant polynucleotides encoding novel na+/h+ antiporters BASF PLANT SCIENCE GMBH (DE) 2004-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507648-B2 Methods and compositions for rapid plant transformation POF1B, IWS1, CCNH KDM4E 4595/4885ALDH1A1 4180/4885GAA 3694/4885
US-20170325457-A1 FORMULATIONS FOR THE DELIVERY OF ACTIVE AGENTS TO INSECTS, PLANTS, AND PLANT PATHOGENS NSF, GET3, SLC47A2 KDM4E 4610/4885ALDH1A1 4714/4885GAA 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.