SCHEMBL29477243

SCHEMBL29477243

C[C@@H]1Cc2cc(O)cc(O)c2C(=O)O[C@H](C)CC(=O)OC[C@@H](O)CC(=O)O[C@H](C)Cc2cc(O)cc(O)c2C(=O)O[C@H](C)CC(=O)O1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
ESR2 Q92731 3/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 2/20 0.50
HSP90AA1 P07900 2/20 0.50
HSP90AB1 P08238 2/20 0.50
POLB P06746 2/20 0.50
NR1I2 O75469 2/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAOA P21397 3/20 0.47
MAOB P27338 2/20 0.47
F13A1 P00488 1/20 0.44
TGM2 P21980 1/20 0.44
KDM4E B2RXH2 1/20 0.43
ESR1 P03372 1/20 0.41
HPGD P15428 1/20 0.41
STAT3 P40763 1/20 0.41
MKNK2 Q9HBH9 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29885475 0.89 MAOA (0.57) LMNASMN1; SMN2ESR2MAPTALDH1A1
SCHEMBL638027 0.83 MAOA (0.64) LMNASMN1; SMN2ESR2MAPTALDH1A1
SCHEMBL2314134 0.71 OPRD1 (0.62) SMN1; SMN2MAPTPOLBMAOAMAOB
SCHEMBL3366271 0.71 OPRD1 (0.62) SMN1; SMN2MAPTPOLBMAOAMAOB
SCHEMBL24210580 0.69 LMNA (0.79) LMNASMN1; SMN2ESR2MAPTALDH1A1
SCHEMBL10150353 0.69 MKNK2 (0.59) LMNASMN1; SMN2ESR2MAPTALDH1A1
SCHEMBL10150349 0.69 MKNK2 (0.65) LMNASMN1; SMN2ESR2MAPTALDH1A1
SCHEMBL10150369 0.69 MKNK2 (0.65) LMNASMN1; SMN2ESR2MAPTALDH1A1
SCHEMBL24210586 0.68 LMNA (0.91) LMNASMN1; SMN2ESR2MAPTALDH1A1
SCHEMBL14182020 0.68 MKNK2 (0.66) LMNASMN1; SMN2ESR2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694906-A1 INFLAMMATION-INDUCIBLE PROMOTERS MeiraGTx Gene Regulation Limited (GB) 2026-02-18 EP disclosed
WO-2024213660-A1 INFLAMMATION-INDUCIBLE PROMOTERS MEIRAGTX UK II LIMITED (GB) 2024-10-17 WO disclosed
US-11600045-B2 Collaborative light show authoring for tessellated geometries CONTRAVENTUM, LLC (US) 2023-03-07 US disclosed
US-20220366648-A1 Collaborative Light Show Authoring for Tessellated Geometries CONTRAVENTUM, LLC (US) 2022-11-17 US disclosed
CN-114806453-A Nano wave absorbing agent and preparation method and application thereof 河南农业大学 2022-07-29 CN disclosed
US-11282276-B2 Collaborative light show authoring for tessellated geometries CONTRAVENTUM, LLC (US) 2022-03-22 US disclosed